A Jmol-based tutorial on the structure of Major Histocompatibility Complex classes I & II proteins is now available at http://MolviZ.Org. This is an enhanced version of the 1998 Chime-based tutorial (which in turn was an enhanced version of a 1995 RasMol Movie Script). The port was accomplished with the Jmol Tutorial-Authoring Template (JTAT, http://www.bioinformatics.org/jmol-tutorials/ ) which has been upgraded to the current release of Jmol (version 12.0.12).
This tutorial is a ready-to-use lesson plan. It includes 21 challenge questions. The questions are shown within the tutorial (in mint green text), and are also available in a .doc file ready to print as handouts for students. Suggestions for lesson structure are included in the .doc file, which is linked in the Contents page of the tutorial. New scenes in this tutorial include: - MHC I colored by evolutionary conservation. (Chapter 4, View 6) - Alignment of an 8 amino acid with a 9 amino acid peptide, as bound in the cleft of the same MHC class I allele. (Chapter 6, View 3) - Side by side comparison of two different viral epitopes in MHC class I (with synchronized rotation; Chapter 6, View 4). - Side by side comparison of epitopes in MHC class I vs. class II. (Chapter 7, View 4) -Eric Special thanks to Bob Hanson for his continued amazing development of Jmol, and for fixing bugs and making changes that I requested, and to Nico Vervelle for promptly releasing each new version. /* - - - - - - - - - - - - - - - - - - - - - - - - - - - Eric Martz, Professor Emeritus, Dept Microbiology U Mass, Amherst -- http://Martz.MolviZ.Org Top Five 3D MolVis Technologies http://Top5.MolviZ.Org 3D Wiki with Scene-Authoring Tools http://Proteopedia.Org Biochem 3D Education Resources http://MolviZ.org See 3D Molecules, Install Nothing! - http://firstglance.jmol.org ConSurf - Find Conserved Patches in Proteins: http://consurf.tau.ac.il Atlas of Macromolecules: http://atlas.molviz.org Workshops: http://workshops.molviz.org World Index of Molecular Visualization Resources: http://molvisindex.org PDB Lite Macromolecule Finder: http://pdblite.org Molecular Visualization EMail List (molvis-list): http://list.molviz.org Protein Explorer - 3D Visualization: http://proteinexplorer.org - - - - - - - - - - - - - - - - - - - - - - - - - - - */ ------------------------------------------------------------------------------ Automate Storage Tiering Simply Optimize IT performance and efficiency through flexible, powerful, automated storage tiering capabilities. View this brief to learn how you can reduce costs and improve performance. http://p.sf.net/sfu/dell-sfdev2dev _______________________________________________ Jmol-users mailing list Jmol-users@lists.sourceforge.net https://lists.sourceforge.net/lists/listinfo/jmol-users
