On 08/08/2013 08:31 PM, Amjad Farooq wrote: > Paul, > > Thanks for your input. But, I do not believe Chimera is a web-based > application. I am looking for a web-based application to perform mutations. > Although an external program might not be web-based you could still use it for doing the mutation.
With the Jena3D viewer (http://jena3d.fli-leibniz.de) we do something similar with Jmol in combination with the 'scap' program from the 'jackal' program package for visualizing known variants (SNPs) in protein structures (e.g. for PDB code 1DEH). Although the amino acid exchanges are usually known beforehand and the mutations are precomputed we also do it on-the-fly if no precomputed mutants are available. Since there might be up to several hundred variants known for a single structure we only load each mutated residue as a separate model and not the whole modeled structure provided by 'scap'. I currently don't have time to go into more detail but if you are interested I could tell you more in about a week. Regards, Rolf -- Rolf Huehne Postdoc Leibniz Institute for Age Research - Fritz Lipmann Institute (FLI) Beutenbergstrasse 11 07745 Jena, Germany Phone: +49 3641 65 6205 Fax: +49 3641 65 6210 E-Mail: rhue...@fli-leibniz.de Website: http://www.fli-leibniz.de Scientific Director: Prof. Dr. K. Lenhard Rudolph Head of Administration: Dr. Daniele Barthel Chairman of Board of Trustees: Dennys Klein VAT No: DE 153 925 464 Register of Associations: No. 230296, Amtsgericht Jena Tax Number: 162/141/08228 ------------------------------------------------------------------------------ Get 100% visibility into Java/.NET code with AppDynamics Lite! It's a free troubleshooting tool designed for production. Get down to code-level detail for bottlenecks, with <2% overhead. Download for free and get started troubleshooting in minutes. http://pubads.g.doubleclick.net/gampad/clk?id=48897031&iu=/4140/ostg.clktrk _______________________________________________ Jmol-users mailing list Jmol-users@lists.sourceforge.net https://lists.sourceforge.net/lists/listinfo/jmol-users
