There was an inspiring related thread a little while ago:

https://groups.google.com/forum/#!searchin/julia-users/graph$20glvisualize/julia-users/ybGrFVKGyDA/KEf6mY0mCwAJ

My impression is that this subject is full of heuristics, and for graphs 
like e.g. the complete Julia package system I believe interactivity is the 
most effective heuristics there is. Compose can't offer that so I have 
simply used a text file with a blacklist of nodes to remove, and a function 
to remove disconnected nodes.

One of the other heuristics to graph layouts is going 3d, projecting your 
nodes on a sphere, a torus etcetera. That's fascinating in itself. You can 
start out with a 2d layout and the spring stiffness model or your own 
variant of it. But if it never settles into a clarifying layout for the 
purpose, you may take that incomplete layout and project it on a spherical 
surface and voila you get clarity. Or a torus. This is quite fun. It's 
neither lightweight nor easy nor fully compatible with Mac OSX, but a more 
complex graph layout application with interactivity could be built using 
the current state of GLVisualize. That state, of course, is changing 
rapidly. 

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