Hi,

here is the solution!

remove pnp_acpi=off and add acpi_iso=Linux
Booted into graphic mode and keyboard and touchpad are working, after 2.5 years

BTW, I am using Ubuntu 19.10 which has nvidia drivers OOTB.

Here is my full grub config:
GRUB_CMDLINE_LINUX_DEFAULT="nomodeset intel_pstate=enable"
GRUB_CMDLINE_LINUX="nogpumanager acpi_iso=Linux"

I will test, if I can remove nomodeset and nogpumanager from the list,
since this were needed on 18.04 LTS...

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https://bugs.launchpad.net/bugs/1584479

Title:
  [MSI GP72 6QE Leopard Pro] acpi=off required to boot

Status in linux package in Ubuntu:
  Incomplete

Bug description:
  Hi,
  I just install Ubuntu 16.04 on my new MSI laptop G72 6QE.
  My touchpad doesn't work and recognize at all.

  I try :
  - Fn+F3 to activate my touchpad
  - xinput list and is not listed
  - xev and nothing append (no signal)
  - cat /proc/bus/input/devices ddoesn't display touchpad (only HDMI, mic, 
headphone, external mouse and keyboard)
  - I don't know if there is a link, but some buttons of my keyboard don't work 
(like Fn+arrows to manage sound and luminosity) :
  I: Bus=0011 Vendor=0001 Product=0001 Version=ab41
  N: Name="AT Translated Set 2 keyboard"
  P: Phys=isa0060/serio0/input0
  S: Sysfs=/devices/platform/i8042/serio0/input/input0
  U: Uniq=
  H: Handlers=sysrq kbd event0 leds 
  B: PROP=0
  B: EV=120013
  B: KEY=600702900000 8380207af040d001 feffffdfffefffff fffffffffffffffe
  B: MSC=10
  B: LED=7

  
  Thanks
  --- 
  ApportVersion: 2.20.1-0ubuntu2
  Architecture: amd64
  AudioDevicesInUse:
   USER        PID ACCESS COMMAND
   /dev/snd/controlC0:  gdm        1305 F.... pulseaudio
                        moi        1668 F.... pulseaudio
  DistroRelease: Ubuntu 16.04
  HibernationDevice: RESUME=UUID=9649bbed-2d32-42cd-a446-43abaa9ab1f3
  InstallationDate: Installed on 2016-05-20 (2 days ago)
  InstallationMedia: Ubuntu-GNOME 16.04 LTS "Xenial Xerus" - Release amd64 
(20160421)
  MachineType: Micro-Star International Co., Ltd. GP72 6QE
  Package: linux (not installed)
  ProcEnviron:
   TERM=xterm-256color
   PATH=(custom, no user)
   LANG=fr_FR.UTF-8
   SHELL=/bin/bash
  ProcFB: 0 inteldrmfb
  ProcKernelCmdLine: BOOT_IMAGE=/@/boot/vmlinuz-4.4.0-22-generic 
root=UUID=80432220-0bdf-49f0-a145-0c015ad36c2a ro rootflags=subvol=@ acpi=off 
acpi_osi=! acpi_backlight=native i8042.nopnp quiet splash
  ProcVersionSignature: Ubuntu 4.4.0-22.40-generic 4.4.8
  PulseList:
   Error: command ['pacmd', 'list'] failed with exit code 1: Home directory not 
accessible: Permission denied
   No PulseAudio daemon running, or not running as session daemon.
  RelatedPackageVersions:
   linux-restricted-modules-4.4.0-22-generic N/A
   linux-backports-modules-4.4.0-22-generic  N/A
   linux-firmware                            1.157
  Tags:  xenial
  Uname: Linux 4.4.0-22-generic x86_64
  UpgradeStatus: No upgrade log present (probably fresh install)
  UserGroups:
   
  _MarkForUpload: True
  dmi.bios.date: 12/10/2015
  dmi.bios.vendor: American Megatrends Inc.
  dmi.bios.version: E1795IMS.10C
  dmi.board.asset.tag: Default string
  dmi.board.name: MS-1795
  dmi.board.vendor: Micro-Star International Co., Ltd.
  dmi.board.version: REV:0.A
  dmi.chassis.asset.tag: Default string
  dmi.chassis.type: 10
  dmi.chassis.vendor: Micro-Star International Co., Ltd.
  dmi.chassis.version: Default string
  dmi.modalias: 
dmi:bvnAmericanMegatrendsInc.:bvrE1795IMS.10C:bd12/10/2015:svnMicro-StarInternationalCo.,Ltd.:pnGP726QE:pvrREV1.0:rvnMicro-StarInternationalCo.,Ltd.:rnMS-1795:rvrREV0.A:cvnMicro-StarInternationalCo.,Ltd.:ct10:cvrDefaultstring:
  dmi.product.name: GP72 6QE
  dmi.product.version: REV:1.0
  dmi.sys.vendor: Micro-Star International Co., Ltd.

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