"One-off as an adjective means 'done, occurring, or made only once', and as
a noun (much less common) 'something that occurs, is done, or is made only
once'. Depending on context, it can be interpreted as meaning 'unique' or
'exceptional', as you suggest; good synonyms are "singular," "unique,"or
"one-shot."

The word stems from the British use of off in commerce to indicate a
quantity of items produced at one time: "Please supply 500 off." A one-off,
then, was an item produced only once, and the current usage is a figurative
application of this technical sense.

One-off is chiefly a Briticism, first found in the 1930s; it has been been
increasingly common in America in recent years." 

Cited from: The Maven's Word of the Day;
http://www.randomhouse.com/wotd/index.pperl?date=19961104

Carole 
Dublin, OH

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