Hello,

Yes, depending on the kind of termination your instrument is
expecting, you have to terminate with the correct termination.  Some
instruments require a carriage return and some require a line feed.
Others will require both.  You need to check with the instrument
manufacturer to determine what kind of termination your instrument is
expecting.  Here is a knowledgebase that describes how to do it in
LabVIEW.

http://digital.ni.com/public.nsf/websearch/862567530005F09C862565BE005AB500?OpenDocument

Good luck!

Regards,
Steven B.
Applications Engineering
National Instruments

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