Ah,  now I see. Thanks!

I tried like below, it seems to work.
TBitmap.LoadFromIntfImage seems to care about the back-conversion, right?

procedure TForm1.Button1Click(Sender:TObject);
var li1,li2:TLazIntfImage;
 Description: TRawImageDescription;
 Row1: PRGBQuadArray;
i:integer;
begin
Li1:=TLazIntfImage.Create(0,0);
Li1.LoadFromDevice(Image1.Canvas.Handle);
Writeln(Li1.DataDescription.AsString);
Description.Init_BPP32_B8G8R8A8_BIO_TTB(Li1.Width,Li1.Height);
Li2:=TLazIntfImage.Create(0,0);
Li2.DataDescription:=Description;
Li2.CopyPixels(Li1);
Row1:=Li2.GetDataLineStart(3);
for i:=0 to 20 do
 begin
   Row1^[i].rgbRed:=$FF;
   Row1^[i].rgbGreen:=$88;
   Row1^[i].rgbBlue:=$88;
 end;

Writeln(Li2.DataDescription.AsString);
Image2.Picture.Bitmap.LoadFromIntfImage(Li2);
end;



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