Hi Andrew,
In this day of gigabyte this an terabyte that, does a large PDF matter
very much? What is the issue of concern?
1. For transferring/emailing, smaller is better for a number of reasons.
2. For those of us (e.g., Music Directors) who store and use multiple
PDFs of complete musicals or operas (and, in the case of workshops, the
associated scripts/libretti) on an iPad, the size of each PDF can make a
huge difference, both in terms of the storage requirements and the
responsiveness within the workflow.
Hope that helps clarify!
Kieren.