And I should mention, as Shane G. suggested, for simple, big, text
processing stuff like this you'll get as good performance from perl as
from compiled code.  There's a reason big text processing genomics stuff
like bioperl is written in perl ....

I'm not a python wizard, but I have to imagine that python should be
similar, performance wise.

-- Pat

On 1/30/13 7:44 AM, John McKown wrote:
> Thanks to all for the input! I _tried_ to run the script over night. I
> added an echo to tell me which input file I was working on. I came in
> this morning. It had been running from 14:00 to 06:30 (16 1/2 hours)
> and was still on the first input file. That ain't gonna cut it. Time
> to rethink. Using a Perl hash to contain an open file handle seems
> logical. As does buffering multiple records per output file to do a
> single I/O to write them. But I may be forced into using C or C++ for
> speed. Too bad I'm not a very good C programmer.
>

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