from the gtk+ 2.2 announcement:

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Support for new X extensions, standards, and libraries:

 GTK+-2.2 adds support for the RANDR extension for screen 
 size changes and for startup notification via a draft 
 freedesktop.org protocol. Interoperability with Qt for 
 inter-application embedding via the XEMBED protocol has 
 been improved. With support for version 2 of the Xft library, 
 antialiased text can be displayed even on older X servers.
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