Hello
We've been running SCCM 2007 on All Virtual machines - 1 Central / 7 Child 
Primaries - ~140,000 clients

We're in the middle of migrating to ConfigMgr 2012 - CAS - 3 Child Primaries - 
All virtual  / ~170,000 clients

Disk latency is a major consideration
Also
SQLServer should be on a different VM - NOT the Site Server!

Hope that helps

From: [email protected] [mailto:[email protected]] On 
Behalf Of Denzik, Josh
Sent: Tuesday, December 08, 2015 7:13 PM
To: [email protected]
Subject: [mssms] System Center Configuration Manager VM VS Physical

All,

I just wanted to ask anyone willing to share their experiences running an 
entire SCCM infrastructure on VM's. I am currently managing approximately 
18,000 machines in our current environment with a physical site server that has 
24 cores and 32 GB of RAM(runs fine).  We are getting ready to build a new site 
after SCCM Vnext comes out with the official production release. Currently we 
have our VM site server spec'd out at 8 Cores with 32 GB of RAM and all the 
necessary storage for sql etc. We are also planning to have a additional MP as 
well. We have fast storage in our data center so that's not an issue. We are 
also worried about growth; and we close to the max our server team can give us 
as far as server cores and ram. This was the recommended hardware 
recommendations updated today per Microsoft 
https://technet.microsoft.com/en-us/library/mt589500.aspx. I am expecting that 
if we go with this VM setup that is should accommodate growth up to at least 
40,000 clients? Is there a secret formula to figure this out? Is Physical the 
preferred method? If anyone can please share their VM specs in a large SCCM 
environment they are running that would be greatly appreciated.


Thanks in Advance!

Joshua Denzik
Senior Systems Engineer | Managed Desktop Team | OCIO-IS




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