The Chicago Manual of Style 14th ed. says:

5.37 An adverbial phrase at the beginning of a sentence is frequently 
followed by a comma.

AND

5.38 The comma is usually omitted after short introductory adverbial phrases 
unless misreading is likely.

I guess you can choose.

Tim Kuntz
>
>>3) Throughout that passage there is a distinct absence of commas,
>>which are used to separate subordinate clauses from the rest of the
>>sentence.
>
>
> Commas are also used to separate introductory phrases.  As "Throughout 
> that
> passage" is an introductory phrase preceding the main clause of the
> sentence, it should also be separated by a comma.
>




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