I generate PDFs using pdflatex from my LyX files. I'm using cm-super; i.e. computer modern Type 1 fonts.
My PDFs look great in Mac OS X Preview, but not-so-great in Adobe Acrobat. The fonts are not well-aligned to the baseline in Acrobat, and unless I magnify to 150% or 200%, the type is misaligned. The glyphs themselves look fine, but they don't follow the baseline properly.
You can avoid this by using the ae fonts (Layout->Document->Font->ae).
ae are Type 1 fonts but note, the glyphs \flq, \frq, flqq and \frqq are not available with ae. You can use \flqq and \frqq anyway, when you install the package 'aeguill' and insert \usepackage[ec]{aeguill} in the preamble.
