Tino Langer schrieb:

I just tried to install lyx on my windows vista. The first problem was to install miketex out of the bundle-installer of lyx 1.4.3-5 (lyx-143-5-bundle.exe ) - an Windows API error occurs. a workaround for this problem was to install miktex 2.5 stand alone and refer to the existing installation while installing lyx.

The MiKTeX shipped with the last installer is not Vista-ready. The next LyX version comes out next week with an updated MiKTeX version.
Note that there are stil some restrictions to use MiKTeX under Vista:
http://dojo.miktex.org/blogs/christian_schenk/archive/2007/01/22/miktex25vista.aspx

But the second problem ist, that I can not start lyx. It seems to be there is no python available. But I thought this application comes with lyx?

Don't you have a python.exe in LyX's \bin directory or somewhere else on your 
computer?

regards Uwe

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