%% LyX 2.0.0svn created this file.  For more info, see http://www.lyx.org/.
%% Do not edit unless you really know what you are doing.
\documentclass[english]{article}
\usepackage{fontspec}
\setmainfont{TeXGyrePagella}

\makeatletter

%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% LyX specific LaTeX commands.
\DeclareRobustCommand{\greektext}{%
  \fontencoding{LGR}\selectfont\def\encodingdefault{LGR}}
\DeclareRobustCommand{\textgreek}[1]{\leavevmode{\greektext #1}}
\DeclareFontEncoding{LGR}{}{}
\DeclareTextSymbol{\~}{LGR}{126}

\makeatother

\usepackage{babel}
\begin{document}
ΨDO
\end{document}