Well, it's being scheduled by launchd, so you should be able to use a tool like 
Lingon or Launch Control to see what jobs you have scheduled.  You can disable 
any of the ones you suspect are causing the problem and reboot, and see if the 
problem goes away or not.

> On Nov 25, 2017, at 11:51 AM, Carl Hoefs <[email protected]> 
> wrote:
> 
> I have a MacPro Tower (MacPro6,1) running Sierra 10.12.6, no external devices 
> connected. When I put it into sleep mode overnight, I can hear that every 4.5 
> minutes, the HDD spins up, there's a disk access, and then it spins down 
> again. I don't like it spinning the HDD up & down all night.
> 
> Looking in the console logs (which has been made so very painful) I believe 
> I've found the culprit:
> 
> Nov 25 03:57:22 com.apple.xpc.launchd[1] (com.apple.quicklook[3691]): 
> Endpoint has been activated through legacy launch(3) APIs. Please switch to 
> XPC or bootstrap_check_in(): com.apple.quicklook
> Nov 25 04:01:57 com.apple.xpc.launchd[1] (com.apple.quicklook[3700]): 
> Endpoint has been activated through legacy launch(3) APIs. Please switch to 
> XPC or bootstrap_check_in(): com.apple.quicklook
> Nov 25 04:04:56 syslogd[52]: ASL Sender Statistics
> 
> The above sequence repeats ad inifitum.
> 
> Does anyone have a clue what this is, and what it thinks it needs to do? 
> 
> -Carl
> 
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