During my first round of grad school I found SPSS to be not accessible with 
JAWS. From what I recall, I do not think any accessibility measures has 
been interjected into the program for screen readers. Some documentation 
exists that does suggest some effort has been previously made with SPSS 14, 
but this was several years ago. I purchased this particular software 
package with no usable results.
However, it has been my experience that the majority of statistical 
computations can be accomplished with Microsoft Excel. (The output is not 
as esthetic, but manageable).
In some cases I have worked with fellow colleagues to complete assignments, 
devise an alternative course of action with professors, and have even hired 
others to help sort and simplify large amounts of raw data for thesis work.

hope this has been helpful

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