I think that except for the network settings area, all settings on the 
Macintosh become active immediately. Certainly I have had no delay in the 
keyboard shortcuts area. 

When there were issues it was usually a bad plist file in the  
Library/Preferences folder. Try changing the setting one more time and then 
immediately exiting System Preferences. If the change did not take effect 
again, I can find the appropriate plist file that might be causing issues.


                Best wishes,

Jonathan Cohn



> On May 6, 2017, at 11:10 PM, Angus MacKinnon <[email protected]> wrote:
> 
> Every time I press down arrow, I get the Accessibility Menu. I have gone to 
> System Prefrences + Keyboard + Shorrtcuts + Accessibility and changed the 
> setting and a few minutes late the setting in Acesassibility is back. How do 
> I save my choices, so my choices stay perment? Thank you. I use OS 10.11.6 on 
> my iMac.
> 
> Angus MacKinnon
> 
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