On 06/25/2012 06:36 AM, Anne Wilson wrote:
Plain M2 :-)  Every time I started Thunderbird I got a message that it
couldn't locate the local mail spool (can't remember the exact words).
  Assuming it meant /var/spool/mail/anne, I touched that, owned
anne:mail (I tried root, too), but now the message is "Unable to
truncate spool file /var/spool/mail/anne".

Try running TB under strace, e. g.

   strace -f -o /tmp/strace -e trace=open,read,write thunderbird

and check the /tmp/strace output for an open or I/O error related to that file after the error occurs.

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