Mailman has been running well for months.  All of a sudden no traffic is not 
going out.  /var/log/maillog shows no errors.
Mailman's smtp-failure shows:

Sep 19 13:31:32 2011 (1215) delivery to [email protected] failed with code 
-1: (101, 'Network is unreachable')
Sep 19 13:31:32 2011 (1215) delivery to [email protected] failed with code 
-1: (101, 'Network is unreachable')
Sep 19 13:31:35 2011 (1215) Low level smtp error: (101, 'Network is 
unreachable'), msgid: <[email protected]>
Sep 19 13:31:35 2011 (1215) delivery to [email protected] failed with code -1: 
(101, 'Network is unreachable')
Sep 19 13:31:38 2011 (1215) Low level smtp error: (101, 'Network is 
unreachable'), msgid: <[email protected]>
Sep 19 13:31:38 2011 (1215) delivery to [email protected] failed 
with code -1: (101, 'Network is unreachable')
Sep 19 13:31:47 2011 (1215) Low level smtp error: (101, 'Network is 
unreachable'), msgid: 
<[email protected]>
Sep 19 13:31:47 2011 (1215) delivery to [email protected] failed with code -1: 
(101, 'Network is unreachable')
Sep 19 13:31:47 2011 (1215) delivery to [email protected] failed with code -1: 
(101, 'Network is unreachable')
Sep 19 13:31:47 2011 (1215) delivery to [email protected] failed with code -1: 
(101, 'Network is unreachable')

I can ping and telnet to the upstream mail agent.
This seems to have just started happening this morning.  Upstream mail agent is 
an exchange system front end.  Exchange is running fine, etc.
Exchange guy is looking at logs...

Any ideas anyone ?

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