Part of asking the question was to learn whether mailman has any ability to verify addresses
I expect the biggest problem to be mobile users who post from multiple IP addresses. I'm somewhat bleeding edge ;) for setting up my home server for SMTP AUTH and sending all my mail through that. Many ISP's and commercial entities are starting to do this as a means of spam control.
I'm also running the MIMEDefang milter under sendmail on all mail going through the box, so all list posts first have to navigate SpamAssassin and ClamAV before getting to Mailman. That has a good chance of trapping the obvious spam and hostile attachments.
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