A review of Brucella infection in marine mammals, with special emphasis on 
Brucella pinnipedialis in the hooded seal (Cystophora cristata)

Ingebjorg H. Nymo, Morten Tryland and Jacques Godfroid



Veterinary Research 2011, 42:93 doi:10.1186/1297-9716-42-93

http://www.veterinaryresearch.org/content/42/1/93/abstract



Brucella spp. were isolated from marine mammals for the first time in 1994. Two 
novel species were later included in the genus; Brucella ceti and Brucella 
pinnipedialis, with cetaceans and seals as their preferred hosts, respectively. 
Brucella spp. have since been isolated from a variety of marine mammals. 
Pathological changes, including lesions of the reproductive organs and 
associated abortions, have only been registered in cetaceans. The zoonotic 
potential differs among the marine mammal Brucella strains. Many techniques, 
both classical typing and molecular microbiology, have been utilised for 
characterisation of the marine mammal Brucella spp. and the change from the 
band-based approaches to the sequence-based approaches has greatly increased 
our knowledge about these strains. Several clusters have been identified within 
the B. ceti and B. pinnipedialis species, and multiple studies have shown that 
the hooded seal isolates differ from other pinniped isolates. We describe!
  how different molecular methods have contributed to species identification 
and differentiation of B. ceti and B. pinnipedialis, with special emphasis on 
the hooded seal isolates. We further discuss the potential role of B. 
pinnipedialis for the declining Northwest Atlantic hooded seal population.

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