Dear colleagues

We are pleased to announce the publication of the following paper:

*Brucella ceti** and brucellosis in cetaceans*

Guzmán-Verri C, González-Barrientos R, Hernández-Mora G, Morales J-A,
Baquero-Calvo E, Chaves-Olarte E and Moreno E (2012) *Brucella ceti* and
brucellosis in cetaceans. Front. Cell. Inf. Microbio. 2:3. doi:
10.3389/fcimb.2012.00003

ABSTRACT

Since the first case of brucellosis detected in a dolphin aborted fetus, an
increasing number of *Brucella ceti* isolates has been reported in members
of the two suborders of cetaceans: Mysticeti and Odontoceti. Serological
surveys have shown that cetacean brucellosis may be distributed worldwide
in the oceans. Although all *B. ceti* isolates have been included within
the same species, three different groups have been recognized according to
their preferred host, bacteriological properties, and distinct genetic
traits: *B. ceti* dolphin type, *B. ceti* porpoise type, and *B.
ceti*human type. It seems that
*B. ceti* porpoise type is more closely related to *B. ceti* human isolates
and *B. pinnipedialis* group, while B. ceti dolphin type seems ancestral to
them. Based on comparative phylogenetic analysis, it is feasible that the *B.
ceti* ancestor radiated in a terrestrial artiodactyl host close to the
Raoellidae family about 58 million years ago. The more likely mode of
transmission of *B. ceti* seems to be through sexual intercourse, maternal
feeding, aborted fetuses, placental tissues, vertical transmission from
mother to the fetus or through fish or helminth reservoirs. The *B.
ceti*dolphin and porpoise types seem to display variable virulence in
land
animal models and low infectivity for humans. However, brucellosis in some
dolphins and porpoises has been demonstrated to be a severe chronic
disease, displaying significant clinical and pathological signs related to
abortions, male infertility, neurobrucellosis, cardiopathies, bone and skin
lesions, strandings, and death.



The pdf is available at the journal site:
http://www.frontiersin.org/cellular_and_infection_microbiology/10.3389/fcimb.2012.00003/abstract

Address for pdf requests : [email protected]

Cheers,

Gabriela



Gabriela Hernández Mora, D.V.M, M.S.c

Microbiología Médico Veterinaria

Servicio Nacional Salud Animal (SENASA)

Costa Rica

+506 25 87 16 00 ext 2092

+506 88 93 76 09
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