Dear colleagues,
We are very happy to share our most recent publication on the "Pathological Studies and Postmortem Computed Tomography of Dolphins with Meningoencephalomyelitis and Osteoarthritis Caused by Brucella ceti" You will find the open-access publication at: *https://www.mdpi.com/2673-1924/3/2/14 <https://www.mdpi.com/2673-1924/3/2/14>* Granados-Zapata, A.; Robles-Malagamba, M.J.; González-Barrientos, R.; Kot, B.C.-W.; Barquero-Calvo, E.; Cordero-Chavaría, M.; Suárez-Esquivel, M.; Guzmán-Verri, C.; Palacios-Alfaro, J.D.; Tien-Sung, C.; Moreno, E.; Hernández-Mora, G. Pathological Studies and Postmortem Computed Tomography of Dolphins with Meningoencephalomyelitis and Osteoarthritis Caused by *Brucella ceti*. *Oceans* 2022, *3*, 189-203. https://doi.org/10.3390/oceans3020014 *Abstract* Cetacean neurobrucellosis is a common cause of strandings in Costa Rica diagnosed by serology, bacteriology, and histopathology. Pathological studies were performed on 18 dolphins. Twelve were scanned by postmortem computed tomography (PMCT) as a complementary tool for describing neurobrucellosis and osteoarticular alterations associated with Brucella ceti infections. The central nervous system (CNS) and the skeleton of five dolphins not infected with B ceti did not reveal alterations by PMCT scanning. Seven Brucella-infected dolphins showed at least bilateral ventriculomegaly associated with hydrocephalus and accumulation in CSF in the lateral ventricles. We performed semiquantitative grading of the inflammatory process in the different areas of the CNS and evaluated the thickness of the cellular infiltrate in the meninges and the perivascular cuffs. The results for the severity grading were graphed to provide an injury profile associated with each area of the CNS. Age is not a decisive factor regarding neurobrucellosis presentation. The severity of ventriculomegaly by PMCT does not directly correlate with the severity of the inflammatory index determined by histopathological parameters of the brain cortex and other CNS regions, suggesting that these processes, although linked, are multifactorial and need further characterization and validation to establish better cutoffs on the PMCT Please feel free to contact us for any questions you may have. Best regards, Gabriela Hernández -- Gabriela Hernández Mora, PhD, M.Sc, DVM Coordinadora Laboratorio de Bacteriología Servicio Nacional de Salud Animal, SENASA Costa Rica Tel +506 25871837 [email protected] [email protected] Skype: gabbytica https://iwc.int/management-and-conservation/strandings/expert-advisory-panel-on-strandings Gabriela Hernández Mora PhD, M.Sc, DVM Chief Bacteriology Laboratory National Service of Animal Health, SENASA SENASA-Costa Rica Tel +506 25871837 [email protected] [email protected] Skype: gabbytica https://iwc.int/management-and-conservation/strandings/expert-advisory-panel-on-strandings
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