I was able to build matplotlib on 64-bit OSX 10.5 just using setup.py. There 
were some glitches, but if I remember correctly they were due to the underlying 
libraries being 32-bits rather than 64-bits. One thing to try is to run "otool 
-L 
/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/_png.so"
 to find out which libraries _png.so uses, and to make sure they are 64-bits 
versions.

--Michiel.

--- On Wed, 12/16/09, Christopher Fonnesbeck <fonnesb...@maths.otago.ac.nz> 
wrote:

> From: Christopher Fonnesbeck <fonnesb...@maths.otago.ac.nz>
> Subject: [Matplotlib-users] matplotlib._png failure on 64-bit OSX
> To: matplotlib-users@lists.sourceforge.net
> Date: Wednesday, December 16, 2009, 1:45 AM
> I have built matplotlib from svn on
> OSX 10.6, using the make.osx script that is included with
> the source, except with the 32-bit build flags removed. The
> resulting module fails on import, however, with the
> following:
> 
> In [1]: from pylab import *
> ------------------------------------------------------------
> Traceback (most recent call last):
>   File "<ipython console>", line 1, in
> <module>
>   File
> "/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/pylab.py",
> line 1, in <module>
>     from matplotlib.pylab import *
>   File
> "/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/pylab.py",
> line 206, in <module>
>     from matplotlib import mpl  # pulls in
> most modules
>   File
> "/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/mpl.py",
> line 2, in <module>
>     from matplotlib import axis
>   File
> "/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/axis.py",
> line 14, in <module>
>     import matplotlib.text as mtext
>   File
> "/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/text.py",
> line 30, in <module>
>     from matplotlib.backend_bases import
> RendererBase
>   File
> "/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/backend_bases.py",
> line 40, in <module>
>     import matplotlib.textpath as textpath
>   File
> "/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/textpath.py",
> line 9, in <module>
>     from matplotlib.mathtext import
> MathTextParser
>   File
> "/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/mathtext.py",
> line 52, in <module>
>     import matplotlib._png as _png
> ImportError:
> dlopen(/Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/_png.so,
> 2): Symbol not found: _png_create_info_struct
>   Referenced from:
> /Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/_png.so
>   Expected in: flat namespace
>  in
> /Library/Python/2.6/site-packages/matplotlib-1.0.svn_r8034-py2.6-macosx-10.6-universal.egg/matplotlib/_png.so
> 
> 
> This seems like this is related to 32-bit code lurking
> somewhere, but I'm not sure where. I am surely using 64-bit
> python.
> 
> Any ideas or solutions are appreciated.
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