I have this script that uses the matplotlib Slider object to control the
colormap of a histogram. This could be very close to what you want. Here is
the script:

### begin colormap_slider.py #################################
import math, copy
import numpy
from matplotlib import pyplot, colors, cm
from matplotlib.widgets import Slider

def cmap_powerlaw_adjust(cmap, a):
    '''
    returns a new colormap based on the one given
    but adjusted via power-law:

    newcmap = oldcmap**a
    '''
    if a < 0.:
        return cmap
    cdict = copy.copy(cmap._segmentdata)
    fn = lambda x : (x[0]**a, x[1], x[2])
    for key in ('red','green','blue'):
        cdict[key] = map(fn, cdict[key])
        cdict[key].sort()
        assert (cdict[key][0]<0 or cdict[key][-1]>1), \
            "Resulting indices extend out of the [0, 1] segment."
    return colors.LinearSegmentedColormap('colormap',cdict,1024)

def cmap_center_adjust(cmap, center_ratio):
    '''
    returns a new colormap based on the one given
    but adjusted so that the old center point higher
    (>0.5) or lower (<0.5)
    '''
    if not (0. < center_ratio) & (center_ratio < 1.):
        return cmap
    a = math.log(center_ratio) / math.log(0.5)
    return cmap_powerlaw_adjust(cmap, a)

def cmap_center_point_adjust(cmap, range, center):
    '''
    converts center to a ratio between 0 and 1 of the
    range given and calls cmap_center_adjust(). returns
    a new adjusted colormap accordingly
    '''
    if not ((range[0] < center) and (center < range[1])):
        return cmap
    return cmap_center_adjust(cmap,
        abs(center - range[0]) / abs(range[1] - range[0]))


if __name__ == '__main__':
    ### create some 2D histogram-type data
    def func3(x,y):
        return (1- x/2 + x**5 + y**3)*numpy.exp(-x**2-y**2)
    x = numpy.linspace(-3.0, 3.0, 60)
    y = numpy.linspace(-3.0, 3.0, 60)
    X,Y = numpy.meshgrid(x, y)
    Z = func3(X, Y)
    extent = [x[0],x[-1],y[0],y[-1]]


    plotkwargs = {
        'extent' : extent,
        'origin' : 'lower',
        'interpolation' : 'nearest',
        'aspect' : 'auto'}

    ### interactively adjustable with a slider
    fig = pyplot.figure(figsize=(6,4))
    fig.subplots_adjust(top=0.8)
    ax = fig.add_subplot(1,1,1)
    cmap = cm.seismic
    plt = ax.imshow(Z, cmap=cmap, **plotkwargs)
    cb = fig.colorbar(plt, ax=ax)

    axcmap = fig.add_axes([0.1, 0.85, 0.8, 0.05], axisbg='white')
    scmap = Slider(axcmap, '', 0.0, 1.0, valinit=0.5)

    def update(val):
        cmapcenter = scmap.val
        plt.set_cmap(cmap_center_adjust(cmap, cmapcenter))
    scmap.on_changed(update)



    pyplot.show()
### end colormap_slider.py ###################################
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