Hi Manal,

On Tue, 2013-07-16 at 18:31 +0200, Manal Farid wrote:
> how XFMA file can be converted to nexus or phylip for further
> phylogenetic analysis
> 
This can be done, but might require some scripting on your part. Each
"block" in the XMFA file is an aligned segment. In principle these could
be concatenated to a single very large alignment using a custom script
and then used for phylogenetic analysis. Depending on which genomes
you've aligned, it might make more sense to extract just the core genome
using a program like stripSubsetLCBs first, and then create a
concatenate of the core genome. See here for some brief instructions on
using stripSubsetLCBs:
http://code.google.com/p/clonalorigin/wiki/FromGenomeAssemblyToRecombination

I don't have any XMFA->phylip or nexus conversion tools but perhaps
somebody else has created such a program? Note that there is an xmfa2maf
tool, so if maf->phylip or nexus exists that might be a possibility.

best,
-Aaron


-- 
Aaron E. Darling, Ph.D.
Associate Professor, ithree institute
University of Technology Sydney
Australia

http://darlinglab.org
twitter: @koadman



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