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Postgraduate Researcher Position at UCSF

We are recruiting a full-time salaried research assistant to work in=20
the laboratory of Dr. Donald M. McDonald, who holds appointments in the
Department of Anatomy (Professor), Cardiovascular Research Institute
(Investigator), and Comprehensive Cancer Institute at UCSF.  The focus
of the lab's research is vascular biology, with particular interests in
angiogenesis and vascular remodeling in  inflammation.  Specifically,
we are investigating (1) cellular mechanisms involved in angiogenesis,
lymphangiogenesis and microvascular remodeling in animal models of
chronic airway inflammation; (2) abnormal features of endothelial cells
and other vascular cells of angiogenic and remodeled blood vessels,
including changes in vascular permeability and expression of novel
proteins; and (3) strategies of targeting abnormal endothelial cells of
blood vessels in tumors and inflamed tissues, with the eventual goal of
targeting the delivery of therapeutics or diagnostics to sites of
disease.  The major disciplines represented in this research are cell
biology, pathophysiology, immunology, and molecular biology.

The experiments in the laboratory involve the use of mouse models of
cancer and chronic inflammation.  In many experiments, tissues are
analyzed by a variety of morphological and immunohistochemical
techniques using light, fluorescence, confocal, and electron
microscopy.

After a training period, the successful applicant will perform
experiments independently.  The postgraduate researcher will also be
responsible for ordering mice and reagents, caring for animals,
preparing buffers and general laboratory upkeep, writing experimental
protocols, and administering drugs to mice, as well as performing
surgery, removing and processing tissues, making morphometric
measurements, and analyzing results.

These responsibilities often require work in excess of 8 hours per day
and occasionally on weekends.  However, if the applicant is
self-motivated, knows how to prioritize, enjoys learning, interacts
well with persons of different backgrounds, and can manage occasional
inevitable technical setbacks, the job provides an excellent learning
experience.

The positions are available in the late spring or early summer of 2006.
   At the latest, the new research assistants should plan to begin work
in early June.  Although a two-year commitment is essential, the job is
temporary in that it is assumed that the applicants will eventually
attend medical school or graduate school.

In general, we are looking for highly motivated students who have a
strong science background.  Oral and written language skills, effective
interpersonal skills, and computer skills are also very important.  No
prior research experience is required, but it would be an obvious
advantage.

Interested students should submit their resume to Rachel Davis at the
e-mail below.  Resumes should include science and math courses
completed, prior research and work experience, career objectives (M.D.,
Ph.D., or both), MCAT or GRE exams taken and scores, earliest possible
starting date, names and contact information for three references, and
desired date of matriculation into medical or graduate school.

Rachel Davis, Shaun O'Brien and Scott Norberg
E-mail: [EMAIL PROTECTED], [EMAIL PROTECTED],
[EMAIL PROTECTED]

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Anne Aaboe                               phone:  (510) 643-7473
Undergraduate Advising Manager                          fax:  (510) 643-2208
Molecular & Cell Biology                          email:  [EMAIL PROTECTED]
2083 Valley Life Sciences, #3200        web:  mcb.berkeley.edu/undergrad
Berkeley, CA 94720
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