September 7, 2008

When Academia Puts Profit Ahead of Wonder
By JANET RAE-DUPREE
NY Times

http://www.nytimes.com/2008/09/07/technology/07unbox.html?_r=1&oref=slogin&ref=business&pagewanted=print


“It is the policy and objective of the Congress to use the patent system to 
promote the utilization of inventions arising from federally supported 
research or development” and “to promote collaboration between commercial 
concerns and nonprofit organizations, including universities.” — The 
Bayh-Dole Act, a k a the University Small Business Patent Procedures Act


THE law of unintended consequences is perhaps less a “law” than a simple 
statement of fact: We cannot accurately predict all the results of our 
actions. We may do something with the best of intentions, and sometimes 
even accomplish the good toward which we aim. Yet, at the same time, we are 
all too often surprised by results that didn’t occur to us beforehand.

The Bayh-Dole Act of 1980 started out with the best of intentions. By 
clearing away the thicket of conflicting rules and regulations at various 
federal agencies, it set out to encourage universities to patent and 
license results of federally financed research. For the first time, 
academicians were able to profit personally from the market transfer of 
their work. For the first time, academia could be powered as much by a 
profit motive as by the psychic reward of new discovery.

University “tech transfer” offices have boomed from a couple dozen before 
the law’s passage to nearly 300 today. University patents have leapt a 
hundredfold. Professors are stepping away from the lab and lecture hall to 
navigate the thicket of venture capital, business regulations and 
commercial competition.

None of these are necessarily negative outcomes. But more than a 
quarter-century after President Jimmy Carter signed it into law, the 
Bayh-Dole Act, sponsored by the former Senators Birch Bayh, Democrat of 
Indiana, and Robert Dole, Republican of Kansas, is under increasing 
scrutiny by swelling ranks of critics. The primary concern is that its 
original intent — to infuse the American marketplace with the fruits of 
academic innovation — has also distorted the fundamental mission of 
universities.

In the past, discovery for its own sake provided academic motivation, but 
today’s universities function more like corporate research laboratories. 
Rather than freely sharing techniques and results, researchers increasingly 
keep new findings under wraps to maintain a competitive edge. What used to 
be peer-reviewed is now proprietary. “Share and share alike” has devolved 
into “every laboratory for itself.”

In trying to power the innovation economy, we have turned America’s 
universities into cutthroat business competitors, zealously guarding the 
very innovations we so desperately want behind a hopelessly tangled web of 
patents and royalty licenses.

Of course, there is precedent for scientific secrecy, notes Daniel S. 
Greenberg , author of “Science for Sale: The Perils, Rewards and Delusions 
of Campus Capitalism” (University of Chicago Press, 2007). When James 
Watson and Francis Crick were homing in on DNA’s double-helix structure in 
the 1950s, they zealously guarded their work from prying eyes until they 
could publish their findings, to be certain that they would get the credit 
for making the discovery.

“They didn’t try to patent it,” Mr. Greenberg notes, “but somebody doing 
the same work today would certainly take a crack at patenting the double 
helix.”

In fact, it was the life sciences — in particular, biotechnology — that 
started universities down the slippery commercial slope in the first place. 
Even before the Bayh-Dole Act, pharmaceutical companies were eagerly 
trolling campuses, looking for projects to finance. After the law was 
passed, they stepped up their efforts, but now with renewed zeal for 
keeping potential trade secrets from competitors.

While patients have benefited from the growing supply of new medications, 
the universities have obtained patents not only for the actual substances 
but also for the processes and methods used to make them, potentially 
hampering discovery of even more beneficial treatments.

“Bayh-Dole tore down the taboos that existed against universities engaging 
in overtly commercial activity. Universities really thought that they were 
going to make it rich,” said Jennifer Washburn, author of “University Inc.: 
The Corporate Corruption of Higher Education” (Basic Books, 2005). “Each 
school was convinced that if they came up with that one blockbuster 
invention, they could solve all their financial problems.”

Ms. Washburn says that was “extremely wrong-headed.” Initially reacting to 
the law by slapping patents on every possible innovation, universities 
quickly discovered that patents were an expensive proposition. The fees and 
legal costs involved in obtaining a single patent can run upward of 
$15,000, and that doesn’t count the salaries of administrative staff 
members. Instead of bringing home the bacon, university tech transfer 
offices were throwing money into the void with little hope of returns.

To date, Ms. Washburn says, data gathered by the Association of University 
Technology Managers, a trade group, show that fewer than half of the 300 
research universities actively seeking patents have managed to break even 
from technology transfer efforts. Instead, two-thirds of the revenue 
tracked by the association has gone to only 13 institutions.

Part of the problem has been a lingering misunderstanding about where the 
value lies in innovation. Patenting a new basic science technique, or 
platform technology, puts it out of the reach of graduate students who 
might have made tremendous progress using it.

Similarly, exclusive licensing of a discovery to a single company thwarts 
that innovation’s use in any number of other fields. R. Stanley Williams, a 
nanotechnologist from Hewlett-Packard, testified to Congress in 2002 that 
much of the academic research to which H.P. has had difficulty gaining 
access could be licensed to several companies without eroding its 
intellectual property value.

“Severe disagreements have arisen over conflicting interpretations of the 
Bayh-Dole Act,” he said. “Large U.S.-based corporations have become so 
disheartened and disgusted with the situation, they are now working with 
foreign universities, especially the elite institutions in France, Russia 
and China.”

THE issue is further clouded by “reach through” licenses, complex 
arrangements used by many tech transfer offices. A reach-through lets the 
patent holder claim a share of any profits that result from using, say, an 
enabling technology, even if those profits come several steps down the 
market transfer line. Several universities are already embroiled in messy 
lawsuits trying to sort out who is entitled to what.

Perhaps the most troublesome aspect of campus commercialization is that 
research decisions are now being based on possible profits, not on the 
inherent value of knowledge. “Blue sky” research — the kind of basic 
experimentation that leads to a greater understanding of how the world 
works — has largely been set aside in favor of projects considered to have 
more immediate market potential.

In academia’s continuing pursuit of profit, the wonder of simple 
serendipitous discovery has been left on the curb.


================================
George Antunes, Political Science Dept
University of Houston; Houston, TX 77204
Voice: 713-743-3923  Fax: 713-743-3927
antunes at uh dot edu

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