Maybe they will have a big anti-vaxxer convention. Indoors, of course. With
an open bar.

On Tue, Sep 15, 2020, 12:05 PM Buggered Benzmail via Mercedes <
mercedes@okiebenz.com> wrote:

> Think of it as evolution in action
>
> --FT
> Sent from iPhone
>
> > On Sep 15, 2020, at 12:02 PM, Andrew Strasfogel via Mercedes <
> mercedes@okiebenz.com> wrote:
> >
> > Once one or more vaccines are available I wonder what the antivaxxer
> rate
> > will be.... of people who refuse under any circumstances to get
> inoculated.
> >
> >> On Tue, Sep 15, 2020 at 10:29 AM Dan Penoff via Mercedes <
> >> mercedes@okiebenz.com> wrote:
> >>
> >> This is informative. Thank you!
> >>
> >> -D
> >>
> >>> On Sep 15, 2020, at 10:04 AM, Buggered Benzmail via Mercedes <
> >> mercedes@okiebenz.com> wrote:
> >>>
> >>> Vaccine trials going on now. 3 friends (One immunologist prof who
> >> developed her own antibody tests and is on the biosafety committee at
> the
> >> hospital, another who is MD/PhD on boards of various drug companies and
> >> affiliated with drug development efforts at the hospital, and his wife)
> got
> >> the first Astra Zeneca doses (maybe, 2/3 chance in this trial, others
> are
> >> 50/50) 2 weeks ago locally. Trials were briefly suspended last week
> after a
> >> possibly (but not likely)-related illness in U.K.  But will likely
> resume
> >> maybe this week after NIH give the go-ahead. A/Z are doing trials in
> U.K.
> >> US and Brazil.
> >>>
> >>> I had some beers with my MD/PhD buddy last night and we discussed this
> >> in some detail. They get a second dose likely next week, and blood
> draws to
> >> monitor responses.
> >>>
> >>> There are 2 other trials going on locally too for other vaccines. (The
> >> different vaccines address different biological aspects of the virus, I
> >> forget the specific chemistry he told me but it has to do with the
> >> structure and function of the virus, which is actually pretty nasty and
> >> unique, hence the vaccine challenges and possibly different
> >> effectivenesses).
> >>>
> >>> He says one vaccine would likely give 50-70% immunity, you can take 2
> or
> >> 3 different types and that would boost your likely immunity up pretty
> high
> >> (flu shots are like 70% effective for a comparison) and would last
> maybe a
> >> coupla years as your biology kinda winds down after awhile and forgets
> >> about it.
> >>>
> >>> My immunologist friend is tempted to run her own antibody test on
> >> herself to see if she got the dose or placebo. Or maybe a friend might
> do
> >> it...
> >>>
> >>> I signed up for the A/Z trial with the higher (2/3) dose probability
> and
> >> am waiting to hear in the next coupla weeks after the initial tranche
> (60
> >> people) are observed and the trial resumes. They had 3000 people sign
> up ,
> >> he thinks I have a pretty good chance (nudge nudge wink wink) of getting
> >> invited in. If you get the actual dose, and it actually works, your
> >> immunity would develop over a month or two, it is not necessarily
> >> immediate, which is how these things work. And even if tests don’t show
> you
> >> have the antibodies, you might still have immunity because humans have
> >> different mechanisms (I think he told me there are 3 mechanisms) for
> >> immunity not all of which will show up on the easier tests. So a lot of
> it
> >> is biology and not really “testable” for immediate results.
> >>>
> >>> He figures there should be some strong clinical results over the next
> >> 3-4 months and vaccines should start becoming available in 4-6 months if
> >> all goes well. And again you could take 2 or 3 different vaccines if
> >> available.  Yes it takes time but this is actually pretty accelerated
> given
> >> the biology of it all.
> >>>
> >>> So that is probably as much as anyone knows (dumbed down a bit for my
> >> consumption) coming from someone right in the middle of it all.  I
> think I
> >> got most of it right, there was beer involved...  It was all quite
> >> informative and encouraging, but practically drug development takes time
> >> and this is being accelerated but still trying to maintain safety.
> >>>
> >>> --FT
> >>> Sent from iPhone
> >>>
> >>>> On Sep 15, 2020, at 7:59 AM, Curt Raymond via Mercedes <
> >> mercedes@okiebenz.com> wrote:
> >>>>
> >>>>  What do you give the odds of a vaccine in the next year or so? I
> know
> >> a lot of folks are busting hump to get one but it seems unlikely to me
> >> considering the fastest vaccine ever took 4 years...
> >>>> -Curt
> >>>>
> >>>>  On Tuesday, September 15, 2020, 12:49:57 AM EDT, archer75--- via
> >> Mercedes <mercedes@okiebenz.com> wrote:
> >>>>
> >>>>> On Sun, 13 Sep 2020 16:08:21 +0000
> >>>>> Rick Knoble via Mercedes <mercedes@okiebenz.com> wrote:
> >>>>>
> >>>>> Long time, no hear...
> >>>>
> >>>>> Rick
> >>>>> _______________________________________
> >>>>
> >>>> Hi Rick,
> >>>> I'm still here; enjoying all the activity on Okiebenz.
> >>>> Looking forward to an effective vaccine.
> >>>> Thanks for your concern.
> >>>> Gerry
> >>>>
> >>>> --
> >>>> This email has been checked for viruses by AVG.
> >>>> https://www.avg.com
> >>>>
> >>>>
> >>>> _______________________________________
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> >>>>
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> >>>
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> >>
> >>
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