You **MUST** configure your mail network to reject invalid recipients with a 5xx code at the MX server. The good old days of having a gateway machine that lacks knowledge of valid internal addresses are gone; such an architecture is unsustainable in today's hostile environment.
Now if we can just convince webmasters to allow "+" in their email forms, so we can use throwaway addresses without multiplying the list of valid recipients. I run into too many form writers who restrict the allowed characters in addresses too much, forcing me to either use my unadorned default address or a default entry in virtusertable.
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