No serious difficulties, just some notes on unexpected behavior that might bear investigation.
There were two concerning messages before reboot, neither logged anywhere that I could find: one was about being unable to write bootblocks and the other was an indication that rebooting might not be possible. Rebooting of course worked fine, using the usual UEFI/GPT process. While rebooting worked, it used the 6.7 BOOTX64.EFI; sysupgrade did not update that file in the EFI system partition. The 6.7 version self-identifies on the console as 3.50 (but that doesn't seem to be logged anywhere), and the 6.8 version, subsequently manually copied from 6.8 /usr/mdec, self-identifies as 3.54. The apparently extraneous warnings should probably not be emitted on UEFI.GPT systems as they may lead to confusion. On the other hand, the EFI boot executables probably should be updated (or at minimum, there should be a message encouraging a manual update). dmesg which incorporates boot information from both versions of BOOTX64.EFI (before and after the manual update) follows. I see only two small differences: one about "random" and "good seed", and the other a tiny difference (ca. 0.0014%) in reported CPU frequency. OpenBSD 6.8 (GENERIC) #97: Sun Oct 4 18:00:46 MDT 2020 dera...@amd64.openbsd.org:/usr/src/sys/arch/amd64/compile/GENERIC real mem = 6319570944 (6026MB) avail mem = 6113099776 (5829MB) random: boothowto does not indicate good seed mpath0 at root scsibus0 at mpath0: 256 targets mainbus0 at root bios0 at mainbus0: SMBIOS rev. 3.0 @ 0xec200 (27 entries) bios0: vendor American Megatrends Inc. version "X555LAB.602" date 07/27/2016 bios0: ASUSTeK COMPUTER INC. X555LAB acpi0 at bios0: ACPI 5.0 acpi0: sleep states S0 S3 S4 S5 acpi0: tables DSDT FACP APIC FPDT FIDT ECDT MCFG HPET SSDT UEFI SSDT LPIT ASF! SSDT SSDT SSDT SSDT PCCT SSDT SSDT DMAR BGRT TPM2 MSDM acpi0: wakeup devices PEG0(S4) PEGP(S4) PEG1(S4) PEGP(S4) PEG2(S4) PEGP(S4) RP01(S4) RP02(S4) RP03(S4) RP04(S4) RP06(S4) RP07(S4) RP08(S4) RP05(S4) PXSX(S4) GLAN(S4) [...] acpitimer0 at acpi0: 3579545 Hz, 24 bits acpimadt0 at acpi0 addr 0xfee00000: PC-AT compat cpu0 at mainbus0: apid 0 (boot processor) cpu0: Intel(R) Core(TM) i7-5500U CPU @ 2.40GHz, 2896.21 MHz, 06-3d-04 cpu0: FPU,VME,DE,PSE,TSC,MSR,PAE,MCE,CX8,APIC,SEP,MTRR,PGE,MCA,CMOV,PAT,PSE36,CFLUSH,DS,ACPI,MMX,FXSR,SSE,SSE2,SS,HTT,TM,PBE,SSE3,PCLMUL,DTES64,MWAIT,DS-CPL,VMX,EST,TM2,SSSE3,SDBG,FMA3,CX16,xTPR,PDCM,PCID,SSE4.1,SS E4.2,x2APIC,MOVBE,POPCNT,DEADLINE,AES,XSAVE,AVX,F16C,RDRAND,NXE,PAGE1GB,RDTSCP,LONG,LAHF,ABM,3DNOWP,PERF,ITSC,FSGSBASE,TSC_ADJUST,BMI1,AVX2,SMEP,BMI2,ERMS,INVPCID,RDSEED,ADX,SMAP,PT,SRBDS_CTRL,MD_CLEAR,IBRS,IBPB,ST IBP,L1DF,SSBD,SENSOR,ARAT,XSAVEOPT,MELTDOWN cpu0: 256KB 64b/line 8-way L2 cache cpu0: smt 0, core 0, package 0 mtrr: Pentium Pro MTRR support, 10 var ranges, 88 fixed ranges cpu0: apic clock running at 99MHz cpu0: mwait min=64, max=64, C-substates=0.2.1.2.4.1.1.1, IBE cpu at mainbus0: not configured cpu at mainbus0: not configured cpu at mainbus0: not configured ioapic0 at mainbus0: apid 2 pa 0xfec00000, version 20, 40 pins acpiec0 at acpi0 acpimcfg0 at acpi0 acpimcfg0: addr 0xf8000000, bus 0-63 acpihpet0 at acpi0: 14318179 Hz acpiprt0 at acpi0: bus 0 (PCI0) acpiprt1 at acpi0: bus -1 (PEG0) acpiprt2 at acpi0: bus -1 (PEG1) acpiprt3 at acpi0: bus -1 (PEG2) acpiprt4 at acpi0: bus 1 (RP01) acpiprt5 at acpi0: bus -1 (RP02) acpiprt6 at acpi0: bus 2 (RP03) acpiprt7 at acpi0: bus 3 (RP04) acpiprt8 at acpi0: bus -1 (RP06) acpiprt9 at acpi0: bus -1 (RP07) acpiprt10 at acpi0: bus -1 (RP08) acpiprt11 at acpi0: bus -1 (RP05) acpipci0 at acpi0 PCI0: 0x00000000 0x00000011 0x00000001 "FLT0101" at acpi0 not configured "ATK3001" at acpi0 not configured acpicmos0 at acpi0 acpiac0 at acpi0: AC unit online acpibat0 at acpi0: BAT0 model "ASUS Battery" serial type LIon oem "ASUSTeK" "INT33A1" at acpi0 not configured "PNP0C14" at acpi0 not configured "ATK4002" at acpi0 not configured acpibtn0 at acpi0: LID_ acpibtn1 at acpi0: SLPB "MSFT0101" at acpi0 not configured "INT3400" at acpi0 not configured "INT340F" at acpi0 not configured acpicpu0 at acpi0: C3(200@506 mwait.1@0x60), C2(200@230 mwait.1@0x33), C1(1000@1 mwait.1), PSS acpipwrres0 at acpi0: PG00, resource for PEG0 acpipwrres1 at acpi0: PG01, resource for PEG1 acpipwrres2 at acpi0: PG02, resource for PEG2 acpipwrres3 at acpi0: WRST acpipwrres4 at acpi0: WRST acpipwrres5 at acpi0: WRST acpipwrres6 at acpi0: WRST acpipwrres7 at acpi0: WRST acpipwrres8 at acpi0: WRST acpipwrres9 at acpi0: WRST acpipwrres10 at acpi0: WRST acpitz0 at acpi0: critical temperature is 108 degC acpivideo0 at acpi0: GFX0 acpivout0 at acpivideo0: LCDD cpu0: using VERW MDS workaround (except on vmm entry) cpu0: Enhanced SpeedStep 2896 MHz: speeds: 2401, 2400, 2300, 2100, 2000, 1900, 1700, 1600, 1400, 1300, 1200, 1000, 900, 800, 600, 500 MHz pci0 at mainbus0 bus 0 pchb0 at pci0 dev 0 function 0 "Intel Core 5G Host" rev 0x09 inteldrm0 at pci0 dev 2 function 0 "Intel HD Graphics 5500" rev 0x09 drm0 at inteldrm0 inteldrm0: msi, BROADWELL, gen 8 azalia0 at pci0 dev 3 function 0 "Intel Core 5G HD Audio" rev 0x09: msi azalia0: No codecs found "Intel Core 5G Thermal" rev 0x09 at pci0 dev 4 function 0 not configured xhci0 at pci0 dev 20 function 0 "Intel 9 Series xHCI" rev 0x03: msi, xHCI 1.0 usb0 at xhci0: USB revision 3.0 uhub0 at usb0 configuration 1 interface 0 "Intel xHCI root hub" rev 3.00/1.00 addr 1 "Intel 9 Series MEI" rev 0x03 at pci0 dev 22 function 0 not configured azalia1 at pci0 dev 27 function 0 "Intel 9 Series HD Audio" rev 0x03: msi azalia1: codecs: Realtek/0x0233 audio0 at azalia1 ppb0 at pci0 dev 28 function 0 "Intel 9 Series PCIE" rev 0xe3 pci1 at ppb0 bus 1 ppb1 at pci0 dev 28 function 2 "Intel 9 Series PCIE" rev 0xe3: msi pci2 at ppb1 bus 2 re0 at pci2 dev 0 function 0 "Realtek 8168" rev 0x10: RTL8168GU/8111GU (0x5080), msi, address 9c:5c:8e:3d:67:56 rgephy0 at re0 phy 7: RTL8251 PHY, rev. 0 ppb2 at pci0 dev 28 function 3 "Intel 9 Series PCIE" rev 0xe3: msi pci3 at ppb2 bus 3 "Atheros AR9485" rev 0x01 at pci3 dev 0 function 0 not configured pcib0 at pci0 dev 31 function 0 "Intel 9 Series LPC" rev 0x03 ahci0 at pci0 dev 31 function 2 "Intel 9 Series AHCI" rev 0x03: msi, AHCI 1.3 ahci0: port 0: 6.0Gb/s ahci0: port 1: 1.5Gb/s scsibus1 at ahci0: 32 targets sd0 at scsibus1 targ 0 lun 0: <ATA, WDC WD20SPZX-22U, 01.0> naa.50014ee21268f2d9 sd0: 1907729MB, 512 bytes/sector, 3907029168 sectors, thin cd0 at scsibus1 targ 1 lun 0: <TSSTcorp, CDDVDW SU-228HB, AS00> removable ichiic0 at pci0 dev 31 function 3 "Intel 9 Series SMBus" rev 0x03: apic 2 int 22 iic0 at ichiic0 spdmem0 at iic0 addr 0x52: 2GB DDR3 SDRAM PC3-12800 SO-DIMM pchtemp0 at pci0 dev 31 function 6 "Intel 9 Series Thermal" rev 0x03 isa0 at pcib0 isadma0 at isa0 pckbc0 at isa0 port 0x60/5 irq 1 irq 12 pckbd0 at pckbc0 (kbd slot) wskbd0 at pckbd0: console keyboard pms0 at pckbc0 (aux slot) wsmouse0 at pms0 mux 0 pcppi0 at isa0 port 0x61 spkr0 at pcppi0 vmm0 at mainbus0: VMX/EPT efifb at mainbus0 not configured uhub1 at uhub0 port 1 configuration 1 interface 0 "GenesysLogic USB2.0 Hub" rev 2.10/4.01 addr 2 uhidev0 at uhub0 port 3 configuration 1 interface 0 "Kensington Kensington Expert Mouse" rev 1.10/2.01 addr 3 uhidev0: iclass 3/1 ums0 at uhidev0: 4 buttons, Z dir wsmouse1 at ums0 mux 0 uvideo0 at uhub0 port 5 configuration 1 interface 0 "04081-0005360016021002455 USB Camera" rev 2.00/0.12 addr 4 video0 at uvideo0 ugen0 at uhub0 port 8 "Generic USB2.0-CRW" rev 2.00/39.60 addr 5 uhub2 at uhub0 port 12 configuration 1 interface 0 "GenesysLogic USB3.0 Hub" rev 3.00/4.01 addr 6 vscsi0 at root scsibus2 at vscsi0: 256 targets softraid0 at root scsibus3 at softraid0: 256 targets root on sd0a (0e60da33d75f54ca.a) swap on sd0b dump on sd0b inteldrm0: 1366x768, 32bpp wsdisplay0 at inteldrm0 mux 1: console (std, vt100 emulation), using wskbd0 wsdisplay0: screen 1-5 added (std, vt100 emulation) syncing disks... OpenBSD 6.8 (GENERIC) #97: Sun Oct 4 18:00:46 MDT 2020 dera...@amd64.openbsd.org:/usr/src/sys/arch/amd64/compile/GENERIC real mem = 6319570944 (6026MB) avail mem = 6113099776 (5829MB) random: good seed from bootblocks mpath0 at root scsibus0 at mpath0: 256 targets mainbus0 at root bios0 at mainbus0: SMBIOS rev. 3.0 @ 0xec200 (27 entries) bios0: vendor American Megatrends Inc. version "X555LAB.602" date 07/27/2016 bios0: ASUSTeK COMPUTER INC. X555LAB acpi0 at bios0: ACPI 5.0 acpi0: sleep states S0 S3 S4 S5 acpi0: tables DSDT FACP APIC FPDT FIDT ECDT MCFG HPET SSDT UEFI SSDT LPIT ASF! SSDT SSDT SSDT SSDT PCCT SSDT SSDT DMAR BGRT TPM2 MSDM acpi0: wakeup devices PEG0(S4) PEGP(S4) PEG1(S4) PEGP(S4) PEG2(S4) PEGP(S4) RP01(S4) RP02(S4) RP03(S4) RP04(S4) RP06(S4) RP07(S4) RP08(S4) RP05(S4) PXSX(S4) GLAN(S4) [...] acpitimer0 at acpi0: 3579545 Hz, 24 bits acpimadt0 at acpi0 addr 0xfee00000: PC-AT compat cpu0 at mainbus0: apid 0 (boot processor) cpu0: Intel(R) Core(TM) i7-5500U CPU @ 2.40GHz, 2896.25 MHz, 06-3d-04 cpu0: FPU,VME,DE,PSE,TSC,MSR,PAE,MCE,CX8,APIC,SEP,MTRR,PGE,MCA,CMOV,PAT,PSE36,CFLUSH,DS,ACPI,MMX,FXSR,SSE,SSE2,SS,HTT,TM,PBE,SSE3,PCLMUL,DTES64,MWAIT,DS-CPL,VMX,EST,TM2,SSSE3,SDBG,FMA3,CX16,xTPR,PDCM,PCID,SSE4.1,SS E4.2,x2APIC,MOVBE,POPCNT,DEADLINE,AES,XSAVE,AVX,F16C,RDRAND,NXE,PAGE1GB,RDTSCP,LONG,LAHF,ABM,3DNOWP,PERF,ITSC,FSGSBASE,TSC_ADJUST,BMI1,AVX2,SMEP,BMI2,ERMS,INVPCID,RDSEED,ADX,SMAP,PT,SRBDS_CTRL,MD_CLEAR,IBRS,IBPB,ST IBP,L1DF,SSBD,SENSOR,ARAT,XSAVEOPT,MELTDOWN cpu0: 256KB 64b/line 8-way L2 cache cpu0: smt 0, core 0, package 0 mtrr: Pentium Pro MTRR support, 10 var ranges, 88 fixed ranges cpu0: apic clock running at 99MHz cpu0: mwait min=64, max=64, C-substates=0.2.1.2.4.1.1.1, IBE cpu at mainbus0: not configured cpu at mainbus0: not configured cpu at mainbus0: not configured ioapic0 at mainbus0: apid 2 pa 0xfec00000, version 20, 40 pins acpiec0 at acpi0 acpimcfg0 at acpi0 acpimcfg0: addr 0xf8000000, bus 0-63 acpihpet0 at acpi0: 14318179 Hz acpiprt0 at acpi0: bus 0 (PCI0) acpiprt1 at acpi0: bus -1 (PEG0) acpiprt2 at acpi0: bus -1 (PEG1) acpiprt3 at acpi0: bus -1 (PEG2) acpiprt4 at acpi0: bus 1 (RP01) acpiprt5 at acpi0: bus -1 (RP02) acpiprt6 at acpi0: bus 2 (RP03) acpiprt7 at acpi0: bus 3 (RP04) acpiprt8 at acpi0: bus -1 (RP06) acpiprt9 at acpi0: bus -1 (RP07) acpiprt10 at acpi0: bus -1 (RP08) acpiprt11 at acpi0: bus -1 (RP05) acpipci0 at acpi0 PCI0: 0x00000000 0x00000011 0x00000001 "FLT0101" at acpi0 not configured "ATK3001" at acpi0 not configured acpicmos0 at acpi0 acpiac0 at acpi0: AC unit online acpibat0 at acpi0: BAT0 model "ASUS Battery" serial type LIon oem "ASUSTeK" "INT33A1" at acpi0 not configured "PNP0C14" at acpi0 not configured "ATK4002" at acpi0 not configured acpibtn0 at acpi0: LID_ acpibtn1 at acpi0: SLPB "MSFT0101" at acpi0 not configured "INT3400" at acpi0 not configured "INT340F" at acpi0 not configured acpicpu0 at acpi0: C3(200@506 mwait.1@0x60), C2(200@230 mwait.1@0x33), C1(1000@1 mwait.1), PSS acpipwrres0 at acpi0: PG00, resource for PEG0 acpipwrres1 at acpi0: PG01, resource for PEG1 acpipwrres2 at acpi0: PG02, resource for PEG2 acpipwrres3 at acpi0: WRST acpipwrres4 at acpi0: WRST acpipwrres5 at acpi0: WRST acpipwrres6 at acpi0: WRST acpipwrres7 at acpi0: WRST acpipwrres8 at acpi0: WRST acpipwrres9 at acpi0: WRST acpipwrres10 at acpi0: WRST acpitz0 at acpi0: critical temperature is 108 degC acpivideo0 at acpi0: GFX0 acpivout0 at acpivideo0: LCDD cpu0: using VERW MDS workaround (except on vmm entry) cpu0: Enhanced SpeedStep 2896 MHz: speeds: 2401, 2400, 2300, 2100, 2000, 1900, 1700, 1600, 1400, 1300, 1200, 1000, 900, 800, 600, 500 MHz pci0 at mainbus0 bus 0 pchb0 at pci0 dev 0 function 0 "Intel Core 5G Host" rev 0x09 inteldrm0 at pci0 dev 2 function 0 "Intel HD Graphics 5500" rev 0x09 drm0 at inteldrm0 inteldrm0: msi, BROADWELL, gen 8 azalia0 at pci0 dev 3 function 0 "Intel Core 5G HD Audio" rev 0x09: msi azalia0: No codecs found "Intel Core 5G Thermal" rev 0x09 at pci0 dev 4 function 0 not configured xhci0 at pci0 dev 20 function 0 "Intel 9 Series xHCI" rev 0x03: msi, xHCI 1.0 usb0 at xhci0: USB revision 3.0 uhub0 at usb0 configuration 1 interface 0 "Intel xHCI root hub" rev 3.00/1.00 addr 1 "Intel 9 Series MEI" rev 0x03 at pci0 dev 22 function 0 not configured azalia1 at pci0 dev 27 function 0 "Intel 9 Series HD Audio" rev 0x03: msi azalia1: codecs: Realtek/0x0233 audio0 at azalia1 ppb0 at pci0 dev 28 function 0 "Intel 9 Series PCIE" rev 0xe3 pci1 at ppb0 bus 1 ppb1 at pci0 dev 28 function 2 "Intel 9 Series PCIE" rev 0xe3: msi pci2 at ppb1 bus 2 re0 at pci2 dev 0 function 0 "Realtek 8168" rev 0x10: RTL8168GU/8111GU (0x5080), msi, address 9c:5c:8e:3d:67:56 rgephy0 at re0 phy 7: RTL8251 PHY, rev. 0 ppb2 at pci0 dev 28 function 3 "Intel 9 Series PCIE" rev 0xe3: msi pci3 at ppb2 bus 3 "Atheros AR9485" rev 0x01 at pci3 dev 0 function 0 not configured pcib0 at pci0 dev 31 function 0 "Intel 9 Series LPC" rev 0x03 ahci0 at pci0 dev 31 function 2 "Intel 9 Series AHCI" rev 0x03: msi, AHCI 1.3 ahci0: port 0: 6.0Gb/s ahci0: port 1: 1.5Gb/s scsibus1 at ahci0: 32 targets sd0 at scsibus1 targ 0 lun 0: <ATA, WDC WD20SPZX-22U, 01.0> naa.50014ee21268f2d9 sd0: 1907729MB, 512 bytes/sector, 3907029168 sectors, thin cd0 at scsibus1 targ 1 lun 0: <TSSTcorp, CDDVDW SU-228HB, AS00> removable ichiic0 at pci0 dev 31 function 3 "Intel 9 Series SMBus" rev 0x03: apic 2 int 22 iic0 at ichiic0 spdmem0 at iic0 addr 0x52: 2GB DDR3 SDRAM PC3-12800 SO-DIMM pchtemp0 at pci0 dev 31 function 6 "Intel 9 Series Thermal" rev 0x03 isa0 at pcib0 isadma0 at isa0 pckbc0 at isa0 port 0x60/5 irq 1 irq 12 pckbd0 at pckbc0 (kbd slot) wskbd0 at pckbd0: console keyboard pms0 at pckbc0 (aux slot) wsmouse0 at pms0 mux 0 pcppi0 at isa0 port 0x61 spkr0 at pcppi0 vmm0 at mainbus0: VMX/EPT efifb at mainbus0 not configured uhub1 at uhub0 port 1 configuration 1 interface 0 "GenesysLogic USB2.0 Hub" rev 2.10/4.01 addr 2 uhidev0 at uhub0 port 3 configuration 1 interface 0 "Kensington Kensington Expert Mouse" rev 1.10/2.01 addr 3 uhidev0: iclass 3/1 ums0 at uhidev0: 4 buttons, Z dir wsmouse1 at ums0 mux 0 uvideo0 at uhub0 port 5 configuration 1 interface 0 "04081-0005360016021002455 USB Camera" rev 2.00/0.12 addr 4 video0 at uvideo0 ugen0 at uhub0 port 8 "Generic USB2.0-CRW" rev 2.00/39.60 addr 5 uhub2 at uhub0 port 12 configuration 1 interface 0 "GenesysLogic USB3.0 Hub" rev 3.00/4.01 addr 6 vscsi0 at root scsibus2 at vscsi0: 256 targets softraid0 at root scsibus3 at softraid0: 256 targets root on sd0a (0e60da33d75f54ca.a) swap on sd0b dump on sd0b inteldrm0: 1366x768, 32bpp wsdisplay0 at inteldrm0 mux 1: console (std, vt100 emulation), using wskbd0 wsdisplay0: screen 1-5 added (std, vt100 emulation)