Hi Philipp,



-          Here comes my first question: Would it be possible to define own 
gradient direction? On the website, you write that the parameters can be 
changed according to the MR sequence-parameters, but I don't find any option to 
change the gradient directions, only the number of directions seems to be 
selectable?


The direction cannot be specified from the GUI, however a typical 
diffusion-weighted image stored in the NRRD format ( *.dwi - there are several 
such images in the DiffusionTestData.zip archive ) contains of a 
meta-information about the gradients similar to the following

DWMRI_b-value:=200.000000
DWMRI_gradient_0000:=0.000000 0.000000 0.000000
DWMRI_gradient_0001:=0.500000 0.500000 0.500000
DWMRI_gradient_0002:=0.000000 0.000000 0.000000

These come from an IVIM dataset with isotropic direction. The specified b-value 
is a reference value and the b-vaules of the gradient images are derived from 
the magnitude of the gradient direction vector. More details can be found here: 
http://www.na-mic.org/Wiki/index.php/NAMIC_Wiki:DTI:Nrrd_format#Describing_DWIs_with_different_b-values

So if you want to specify the directions you have to fill the gradient  meta 
information, the easiest would be to take the generated image ( saved in .hdwi 
format ) and then modify the header file in an text editor.

This also is related to your second question:


-          It would be great if you could give me hint how I could save a whole 
artificial diffusion dataset?

You have to specify some diffusion format ( .dwi, .hdwi, .fslgz ) when saving a 
diffusion image. Otherwise the writer interprets it as a 3D+t image and so it 
is stored. But it is always a single file on the disk.

Best,
Jan



From: Philipp Stämpfli [mailto:[email protected]]
Sent: Montag, 1. Dezember 2014 10:55
To: [email protected]
Cc: [email protected]
Subject: [mitk-users] How to save all volumes of an artificial diffusion dataset

Hello

I try to create an artificial diffusion dataset with MITK. Therefore, I do the 
following steps in MITK diffuison:

-On the Fiberfox-Tab, I go to Signal generation and press Start Simulation
- On the Fiber definition Tab, I define two fiber bundles
- I select these two fiber bundles in the "data-manager window" and then click 
on "join bundles" on the fiber definition tab
- In the signal generation tab, I select the different parameters and also the 
Save-Path-Directory
- Here comes my first question: Would it be possible to define own gradient 
direction? On the website, you write that the parameters can be changed 
according to the MR sequence-parameters, but I don't find any option to change 
the gradient directions, only the number of directions seems to be selectable?
- Finally, I click on Start simulation again... Now, I'd like to save my B0 
image and the 30 (or whatever number of diffusion direction) as nii volumes (or 
analyze or...), but when I click on the created 
Bundle_1+Bundle_0..._StickBall_RELAX entry, only a single volume is saved...
It would be great if you could give me hint how I could save a whole artificial 
diffusion dataset? Thank you very much for your help and support!
Kind regards
Philipp Stämpfli
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