If you go to the “Q-Balls” view in MITK Diffusion, you can also select “Raw 
Signal Only” as reconstruction and you will simply get an interpolation of the 
input signal, albeit with a different number of sampling directions. This is 
maybe good for visualizing what the result looks like.

Von: Neher, Peter [mailto:[email protected]]
Gesendet: Donnerstag, 25. Januar 2018 07:26
An: Tabinda Sarwar <[email protected]>; 
[email protected]
Betreff: Re: [mitk-users] Resampling the signal for tractography using machine 
learning

Hi Tabinda,

this is indeed a bit confusing. We do not calculate actual Q-balls here. The 
analytical qball filter is also capable of only fitting the raw signal with 
spherical harmonics. This is done by setting 
“filter->SetNormalizationMethod(InterpolationFilterType::QBAR_RAW_SIGNAL);”

By the way, please answer to the list so that other users can also read out 
conversation.

Peter

Von: Tabinda Sarwar [mailto:[email protected]]
Gesendet: Donnerstag, 25. Januar 2018 00:38
An: Neher, Peter <[email protected]<mailto:[email protected]>>
Betreff: Re: [mitk-users] Resampling the signal for tractography using machine 
learning

Hi Peter,

The high level details which I can understand is that first from raw input dMRI 
ODF is computed using analytical Q-ball method which undergoes sampling. If I 
am right, doesn't it makes the input features dependent on the ODF computation 
technique?

Tabinda

On Wed, Jan 24, 2018 at 5:45 PM, Neher, Peter 
<[email protected]<mailto:[email protected]>> wrote:
Dear Tabinda,

we interpolate the original signal using spherical harmonics and then sample 
100 directions form this representations:
https://phabricator.mitk.org/source/mitk/browse/master/Modules/DiffusionImaging/FiberTracking/Algorithms/TrackingHandlers/mitkTrackingHandlerRandomForest.cpp;2642ee4902f4b1e8f5c443f22b30aa896795d5da$105

The actual fitting of the spherical harmonics and the sampling is done in this 
class: 
https://phabricator.mitk.org/source/mitk/browse/master/Modules/DiffusionImaging/DiffusionCore/include/Algorithms/Reconstruction/itkAnalyticalDiffusionQballReconstructionImageFilter.h

The number of directions is defined by the template parameter 
NumberOfSignalFeatures of the TrackingHandlerRandomForest class.

Cheers,
Peter

---------------------------------------------------------------------

Dr. Peter F. Neher
Division of Medical Image Computing (MIC)
Scientist

German Cancer Research Center (DKFZ)
Im Neuenheimer Feld 
280<https://maps.google.com/?q=Im+Neuenheimer+Feld+280+%0D+69120+Heidelberg+%0D+Germany&entry=gmail&source=g>
69120 Heidelberg
Germany
Phone: +49 6221 42-2330

[email protected]<mailto:[email protected]>
www.dkfz.de/en/mic/<http://www.dkfz.de/en/mic/>

________________________________________
Von: tabinda 
<[email protected]<mailto:[email protected]>>
Gesendet: Mittwoch, 24. Januar 2018 06:16
An: [email protected]<mailto:[email protected]>
Betreff: [mitk-users] Resampling the signal for tractography using machine 
learning


Hi!

I am reading the paper "Neher, P. F., Côté, M.-A., Houde, J.-C., Descoteaux,
M. & Maier-Hein, K. H. Fiber tractography using machine learning. Neuroimage
158, 417–429 (2017)" and am trying to understand the methodology using the
MITK source code. But I am confused how the input raw signal is resampled to
100 directions? I couldn't locate the source code for this particular step.
I need to know how mathematically this is done?
For example if original data is (140x140x90) is acquired using 30 gradients
(which makes the dMRI 140x140x90x30), resampling causes the dMRI to be of
size 140x140x90x100? Guidance on the resampling will help me to understand
the algorithm. Any help will be highly appreciated.

Thanks and Regards,
Tabinda



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