Who's Python distribution are you using? It is actually the Python distribution 
that looks to be the problem. Doesn't look like it has been configured 
correctly when built such that it can be used in embedded systems. Haven't see 
the problem for many many years and when did was with a packaging system for 
MacOS apps that as far as I know doesn't exist anymore.

Graham

> On 8 Mar 2022, at 7:18 pm, Suraj Shaw <[email protected]> wrote:
> 
> Hi,
>  macOS - Big Sur (11.6.2) . Yes its an Intel System.
> 
> file 
> /Users/apple/.virtualenvs/djangodev/lib/python3.8/site-packages/mod_wsgi/server/mod_wsgi-py38.cpython-38-darwin.so
>  <http://mod_wsgi-py38.cpython-38-darwin.so/>
> /Users/apple/.virtualenvs/djangodev/lib/python3.8/site-packages/mod_wsgi/server/mod_wsgi-py38.cpython-38-darwin.so:
>  Mach-O universal binary with 2 architectures: [x86_64:Mach-O 64-bit bundle 
> x86_64] [arm64:Mach-O 64-bit bundle arm64]
> 
> /Users/apple/.virtualenvs/djangodev/lib/python3.8/site-packages/mod_wsgi/server/mod_wsgi-py38.cpython-38-darwin.so
>  (for architecture x86_64): Mach-O 64-bit bundle x86_64
> 
> /Users/apple/.virtualenvs/djangodev/lib/python3.8/site-packages/mod_wsgi/server/mod_wsgi-py38.cpython-38-darwin.so
>  (for architecture arm64): Mach-O 64-bit bundle arm64
> 
> 
> 
> file /usr/sbin/httpd
> 
> /usr/sbin/httpd: Mach-O universal binary with 2 architectures: [x86_64:Mach-O 
> 64-bit executable x86_64] [arm64e:Mach-O 64-bit executable arm64e]
> 
> /usr/sbin/httpd (for architecture x86_64): Mach-O 64-bit executable x86_64
> 
> 
> /usr/sbin/httpd (for architecture arm64e): Mach-O 64-bit executable arm64e
> 
> 
> 
> which apxs
> 
> 
> apxs not found
> 
> apxs -q BINDIR
> 
> zsh: command not found: apxs
> 
> 
> 
> I have installed mod_wsgi using the command - >     pip install mod_wsgi
> 
> Thanks
> Suraj
> 
> 
> 
> On Tuesday, 8 March, 2022 at 1:27:22 am UTC+5:30 Graham Dumpleton wrote:
> Give the OS version, I presume this is an Intel system?
> 
> What do you get when you run:
> 
>     file 
> /Users/apple/.virtualenvs/djangodev/lib/python3.8/site-packages/mod_wsgi/server/mod_wsgi-py38.cpython-38-darwin.so
>  <http://mod_wsgi-py38.cpython-38-darwin.so/>
> 
> and:
> 
>     file /usr/sbin/httpd
> 
> and:
> 
>     which apxs
> 
> and:
> 
>     apxs -q BINDIR
> 
> Graham
> 
> 
>> On 8 Mar 2022, at 1:50 am, Suraj Shaw <[email protected] 
>> <applewebdata://71C22F82-ED00-4F6E-BB6D-F8759FBA832E>> wrote:
>> 
> 
>> Hi ,
>> I am using the following configuration.I have installed mod_wsgi using pip 
>> command.I am using macos bigSur(11.6.2). 
>> 
>> mod-wsgi==4.9.0
>> 
>> 
>> Server version: Apache/2.4.51 (Unix) - Apple Version
>> 
>> I am getting the following error
>> 
>> 
>> httpd: Syntax error on line 191 of /private/etc/apache2/httpd.conf: Cannot 
>> load 
>> /Users/apple/.virtualenvs/djangodev/lib/python3.8/site-packages/mod_wsgi/server/mod_wsgi-py38.cpython-38-darwin.so
>>  <http://mod_wsgi-py38.cpython-38-darwin.so/> into server: 
>> dlopen(/Users/apple/.virtualenvs/djangodev/lib/python3.8/site-packages/mod_wsgi/server/mod_wsgi-py38.cpython-38-darwin.so
>>  <http://mod_wsgi-py38.cpython-38-darwin.so/>, 10): Library not loaded: 
>> @rpath/Python3.framework/Versions/3.8/Python3\n  Referenced from: 
>> /Users/apple/.virtualenvs/djangodev/lib/python3.8/site-packages/mod_wsgi/server/mod_wsgi-py38.cpython-38-darwin.so
>>  <http://mod_wsgi-py38.cpython-38-darwin.so/>\n  Reason: image not found
>> 
>> Could anyone please guide me on this.
>> 
>> Thanks and Regards 
>> Suraj
>> 
>> 
> 
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