Thank you, Saul!

This was one of my favorite parts:

 Thirteen subjects exhibited abnormal collecting, characterized by
massive and disruptive accumulation of useless objects. In all cases,
the abnormality of collecting behaviour was severe and persisted
despite attempted interventions and obvious negative consequences.
There were no differences between pathological collectors and
non-collectors on tests of executive functions or anterograde memory.
All subjects with pathological collecting behaviour had damage to the
mesial frontal region (including the right polar sector and the
anterior cingulate), but there was no damage to most of the subcortical
structures that, in species such as rodents, are known to drive the
acquisition and retention of objects. The evidence suggests that damage
to the mesial frontal region disrupts a mechanism which normally
modulates subcortically driven predispositions to acquire and collect,
and adjusts these predispositions to environmental context.

I need to email this link to my brother (also a doctor) who sometimes
buys multiple copies of the same book and stacks them all up on his
shelves because he doesn't want the book to sit in the stores unsold!

Nathalie Yafet

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