Hello Mike,

Thank you for your helpful reply. Interesting as indeed the landmark density 
within the blocks of my posted test examples are not huge: ranging from 29 to 
13. I had kept these low being cautious about obtaining inflated r-pls values 
due to sample size/number of landmarks. Out of curiosity, how few where the few 
in your test when you saw proper numeric divergence in the effect values? 

Maybe helpful to know: I have run the same test with the modularity.test 
function, and both sets obtained the exact same results: CR value of 0.7357 
(p=0.001), with effect size of -8.4022. So it does seem to be, or at least in 
my case, confined to multi-block PLS effects.

With best wishes and many thanks,
K.


> On 19 Oct 2020, at 17:57, Mike Collyer <[email protected]> wrote:
> 
> Katrien,
> 
> Changing the order of factor levels can certainly change Z-scores and 
> P-values, but I was surprised that it changed as much as you observed.  The 
> reason it is not constant is because the permutation schedule (random 
> assignment of rows of values) will change with rearrangement of the module 
> blocks.  However, I would expect the differences to be subtle.  
> 
> I was able to recreate something like your scenario (using integration.test) 
> with simulated data but found it only occurred if I had few landmarks per 
> module, suggesting this could be a landmark density issue.  Does that seem 
> consistent with your data (are there only a few landmarks in each of the five 
> modules)?  When I increased the number of landmarks, I got what I expected: 
> different but qualitatively similar Z-scores and P-values.
> 
> Regarding the comapre.pls approach, the pooled standard error is calculated 
> differently, so a 
> change in this case should be expected.
> 
> Hope that is helpful.
> 
> Mike
> 
> 
>> On Oct 19, 2020, at 9:55 AM, Katrien Janin <[email protected] 
>> <mailto:[email protected]>> wrote:
>> 
>> Hey all, 
>> 
>> I hope somebody can help me out to make sense of the following:
>> Example #1 and #2 draw upon the same data set and same partition, just that 
>> the blocks are in reverse order.
>> 
>> #1 > L.sym.nh.int5.pairwise
>>       A    B     C    D     E
>> A  0.000 0.782 0.688 0.756 0.791
>> B  0.782 0.000 0.750 0.879 0.679
>> C  0.688 0.750 0.000 0.723 0.815
>> D  0.756 0.879 0.723 0.000 0.632
>> E  0.791 0.679 0.815 0.632 0.000
>> 
>> #2 > L.sym.nh.int5.pairwise
>>       E    D     C    B     A
>> E  0.000 0.632 0.815 0.679 0.791
>> D  0.632 0.000 0.723 0.879 0.756
>> C  0.815 0.723 0.000 0.750 0.688
>> B  0.679 0.879 0.750 0.000 0.782
>> A  0.791 0.756 0.688 0.782 0.000
>> 
>> both obtain an overall r-PLS: 0.750 (p= 0.001), and as you can see in the 
>> tables the individual pairs obtain the exact same r-pls (as expected).
>> 
>> the odd thing is that their effect size differ: example #1 returns an effect 
>> size of 2.6798 whilst #2 has a effect size of 4.640. 
>> 
>> any ideas what may be causing this? what can I do to find out what creates 
>> this difference in effect size, and which one I can report along the r-pls 
>> values?
>> 
>> 
>> K.
>> 
>> PS. I also computed the pls and effect for each individual pair with 
>> two.block: I yet again obtain the same r-pls values as in tables above (as 
>> expected) and when I average the effects of the pairs as obtained with the 
>> compare function I arrive at 5.626 ... 
>> 
>> 
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