50 mil down ought to do the trick, if you can make it fit; most board houses 
I've worked with require 25 mil copper clearance and 75-100 mil hole clearance 
from the edge.

As far as chips fitting side by side, chips with a multiple of 4 pins (16, 20 
being the most common) can usually fit. The reason 14-pin DIPs have that 
problem is because their bodies extend significantly beyond the outer pins, 
whereas those with an even number of pins per row are usually nearly flush.

> On Feb 28, 2014, at 12:39, Crusty OMO <[email protected]> wrote:
> 
> Paul, The drawing does not show actual trace width.
> 
> Yoda, Those shorted pins above the 5V regulator are for an optional 12V 
> regulator.  I agree, the 5V reg should be moved a little right.
> 
> Dave, Yes, the holes are close to the edge (aren't we all?).
> 
> Right, great questions, let me describe the board. 
> All the traces between the S-100 and Buffer IC's are 12mil with 13mil 
> spacing.  Traces that tie the 74LS245 chip directions to ground or vcc are 
> 8mil.  The board is ready to go as a slave board (ie memory, i/o, etc).  If 
> you need to convert it to a CPU board, the buffer directions need to be 
> reversed, the 8mil traces need to be cut, jumper wires added.  The +5V and 
> Ground traces are 50mil, they extend up the right side of the board and feed 
> every 4th hole (only the top layer is shown, the GND is fed to every 4th hole 
> from the copper side).  From these holes, bus wire can be used to feed a row 
> of 300mil chips.  The +8V is also 50mil to the regulator, but goes through a 
> short 25 mil "fuse" trace.  This way a short will not fry the whole trace and 
> damage the gold plated S-100 pads.     The +16V and -16V use 35mil traces and 
> go through a short 25mil "fuse" trace too (I should reduce this to 20mil).
> 
> The 5V regulator is at the same location where Andrew placed it on the 
> Unbuffered board, but I agree, it should come a little to the right, say 
> 100mil.  Above it are provisions for a +12V and -12V regulator.  The power 
> traces reach those pads, but you don't have to use them.  There's plenty of 
> holes around it so you can easily install any other IC there around the 
> specialized holes for the regulator.  This regulator does not need to move, 
> it will never require a big heat sink... I hope.
> 
> The top row can be made like this, but I agree it's a little too close... I 
> think I'll shift everything down 50mil and sacrifice a row on the bottom.
> 
> The 74LS245 chips can be placed side by side (even on sockets).   I've 
> checked this out with a dozen different chips from my junk box, it works for 
> all of them.  I think the 14 pin chips have this problem, especially those 
> from 1970's.  I can redo this test and take photo's if that helps?

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