And now:Ish <[EMAIL PROTECTED]> writes:

>X-Mailer: AOL 4.0 for Windows 95 sub 214
>Date:         Tue, 22 Dec 1998 08:45:17 EST
>From:         [EMAIL PROTECTED]
>Subject:      [FN] Fwd: Mayan Indigenous Peoples to Participate in Drug...
>To:           [EMAIL PROTECTED]
>
>
>From: [EMAIL PROTECTED]
>Return-path: <[EMAIL PROTECTED]>
>Subject: Mayan Indigenous Peoples to Participate in Drug...
>Date: Tue, 22 Dec 1998 08:41:59 EST
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>Mayan Indigenous Peoples to Participate in Drug Screening Programme; Will
>Catalogue Benefits of Local Herbal Medicines
>
>SLOUGH, United Kingdom, Dec. 22 /PRNewswire/ -- Xenova Group plc (London
Stock
>Exchange: XEN; Nasdaq: XNVAY) today announced that Xenova Discovery, a
>subsidiary of Xenova Group plc, has been awarded a research programme
grant by
>The International Cooperative Biodiversity Groups Programme of the US
National
>Institutes of Health, National Science Foundation and the US Department of
>Agriculture.  Xenova was awarded the grant as part of a joint proposal led by
>the University of Georgia, Athens, Georgia, USA.  El Colegio de la Frontera
>Sur, San Cristobal de Las Casas, Chiapas, Mexico will also participate in the
>programme.
>
>Under the terms of the grant, Xenova Discovery will gain access for the first
>time to the biodiversity of the Chiapas region of Southern Mexico, part of
one
>of the world's most important biodiversity areas, with the long term goal of
>developing new therapeutic agents.  Work will be carried out among and with
>the collaboration of the local Maya-speaking peoples, who utilise hundreds of
>species of plants in an ancient system of traditional medicine. Xenova
>Discovery will undertake the chemical profiling of a comprehensive inventory
>of the flora of Chiapas, with a special emphasis on those medicinal plants
>used extensively by the local populations.  Fungi and actinomycetes,
>especially those associated with rare or endemic plants of the region, will
>also be isolated and fermented. Libraries of extracts and compounds will be
>prepared from selected plants and microbial fermentations, using techniques
>developed by Xenova and adding to the novelty and diversity of Xenova's
>NatChem(TM) library system.  The libraries will then be screened against a
>wide range of targets for pharmaceutical or agrochemical lead discovery.  As
>part of the programme, local Maya collaborators will be trained in
>participatory workshop activities for the isolation and culturing of samples.
>
>The Tzeltal and Tzotzil Maya-speaking populations of the central highlands of
>Chiapas, Mexico, define illnesses by describing their symptoms.  They then
>treat the symptoms of a wide range of diseases, from reproductive problems to
>mental disorders, using a complex understanding of herbal healing which is
>passed on from generation to generation by word of mouth and experience.
>
>The beneficial effects of indigenous medicines are well documented. Aspirin,
>for example, was originally derived from the use of willow bark to treat
fever

>in the European herbal medicines tradition.  "The team has had direct
personal
>experience of the value of the local traditional healing practices," said Dr.
>Neil Robinson, Xenova Discovery's Head of Analytical Chemistry.  "When Dr.
>Elois Ann Berlin, the wife of consortium leader Professor Brent Berlin, and
>her daughter were burned by scalding water, the use of a local remedy --
>application of the sticky balm of the inner leaf of the nopal, a common
>prickly pear cactus -- led to faster healing for herself than for her
>daughter, who was treated with standard modern medical techniques."  Dr.
Elois
>Ann Berlin is also a scientist on the consortium.
>
>The consortium aims to conduct a medical ethnobiology and biodiversity
>inventory of the Highland Region of Chiapas, about a third of the total area
>of the state, and to consider conservation, sustainable harvest and economic
>growth.  The group is currently awaiting completion of negotiations and
>appropriate agreements with the Mexican government for work to proceed.
>
>Other successful award applicants include Glaxo Wellcome, Bristol-Myers
>Squibb, Shaman Pharmaceuticals, American Cyanamid and Monsanto-Searle, all of
>whom will work with academic groups in various areas of special biological
>interest.
>
>Safe Harbor Statement under the US Private Securities Litigation Reform
Act of
>1995: Some or all of the statements in this document that relate to future
>plans, expectations, events, performances and the like are forward- looking
>statements, as defined in the US Private Securities Litigation Reform Act of
>1995.  Actual results of events could differ materially from those described
>in the forward-looking statements due to a variety of factors, including
those
>set forth in the Company's filings with the US Securities and Exchange
>Commission.
>
>SOURCE  Xenova Group plc
>
>CO:  Xenova Group plc; Xenova Discovery; International Cooperative
>Biodiversity Groups Programme of the US National Institutes of Health,
>National Science Foundation and the US Department of Agriculture
>
>ST:  United Kingdom
>
>IN:  MTC
>
>SU:
>
>12/22/98 08:40 EST http://www.prnewswire.com

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