>
> Any particular reason why you dont want to use direct-drive ? There's a 
> slight additional cost, but you eliminate all of the problems with 
> multiplexing (flicker, ghosting, audible noise, less brightness).
>

If PCB size is your concern, then use an HV5530 driver. Even though it's 
surface-mount, it's pretty easy to solder it and 1 device will drive 3 
tubes. My latest clock has six IN-18  tubes, plus all the connectors, 
drivers, level-translator, and current-limiter for each tube on a 8.5" x 
3.25" PCB. Half the PCB area is the IN-18 footprint.

 

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