Yes, I typically use a PMOS device to regulate the current at the anode. 
You can also use a PNP, but the non-zero base-current needs to be 
accounted-for. I drive the gate with an isolated DCDC converter at roughly 
-12V; to make the current adjustable you can use a pot to drive the gate. 
Using a source-resistance of 1.6K ohms, the current is around 5mA. Let me 
know if you want me to post a schematic; I have additional protection for 
ESD and driver-failure.

And, yes, it costs more money to use a current-limiter rather than a simple 
series resistor, but I spend *SO* much $$ for nixie tubes, not to mention 
they are getting rarer, that it's OK for me. I'm sure it's overkill. 

I've also done current-regulation at the cathode side for segmented 
displays; you cant regulate the anode current because it varies based on 
the number of illuminated segments.

One subtle note about the '1' numeral in a nixie tube: It's often 
constructed with 2 adjacent wires and located at the very rear of the tube. 
Though you would expect more brightness from a '1', it's obscured by all of 
the other cathodes in front so it doesn't appear to be much brighter 
compared to the other numerals.

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