I would not use an RC circuit; not only would it be expensive, it would 
require a lot of trial-by-error experimenting and it likely would be 
susceptible to tube-aging and inherent differences between tubes. Stick 
with PWM.

I know for a fact that tubes of the same type, and even with same/similar 
date-code, have different I-V characteristics from data I've gathered on my 
own tubes.

Heat shouldn't be an issue for your drivers, unless you use a really high 
supply voltage or you use multiple devices in a single package. It's easy 
to calculate. For example, if you have a +200V supply, and the tube 
requires 150V to illuminate at 5mA, your driver will dissipate 250mW 
maximum. In reality, you will have anode and/or source/emitter resistors 
that will dissipate some of the ~250mW, so the heat dissipated by the 
driver will be even less.

My first clock is an extreme example: +340V supply, 160V across the nixie, 
leaving 180V across the 75K  anode resistor. That equates to 400mW; I 
played it safe and used 1W resistors instead of 1/2W devices. The driver, 
however, had essentially zero power dissipation because it's either on or 
off.

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