Ah, this is not uncommon. A lot of AVR Dragons were slain for the same 
reason. Touching the regulator affects its feedback and therefore its 
output voltage. A tiny ESD, not enough to cause any damage, can drive the 
output high for enough milliseconds to cook a 3.3V IC downstream.

On Wednesday, December 9, 2020 at 3:33:06 PM UTC-8 nixiebunny wrote:

> The voltage feedback resistor is a low impedance node on every voltage 
> regulator design that I have worked with. Typically 1k ohm. I don't see how 
> that could happen. 
>
>
> On Wed, Dec 9, 2020, 12:30 PM newxito <[email protected]> wrote:
>
>> I just wanted to share something that happened to me yesterday. I killed 
>> the ESP32 on my nixie board just by touching the adjustable voltage 
>> regulator IC with one finger. I’m pretty sure that I touched the feedback 
>> pin causing the voltage to increase. 
>> I already changed the design, and, in the future, I will only use 
>> regulators with fixed output voltage. I hope they are less sensitive.
>>
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