From Meryl Nass:

This is a great story.

The Canadians found something anomalous, but something we know can 
happen from vaccines:
they CAN enhance infections, proven to have happened with some animal vaccines.

The rest of the world is doing their best to pretend this study never 
happened.  (I wonder if
anyone is trying to repeat it with other datasets, or if they are too 
scared to try?)

And Canada is being totally logical.  If swine flu is so much more of 
a problem than seasonal
flu, and if there is so little seasonal flu currently circulating, 
let's not take a chance damaging
our immunity to swine flu by vaccinating for an illness (seasonal 
flu) we probably don't need
to vaccinate for, since virtually only the elderly die, and we 
vaccinate everyone else to save them
. . . 'cause the elderly mount poor immune responses to flu vaccines. 
 (The population doesn't
know that is much of the rationale for giving kids flu shots.)  So 
restrict seasonal flu shots to
those over 65.  Excellent logic.

I wonder if the story will be blacked out in future?

Meryl

Study prompts provinces to rethink flu plan
Patrick White

Winnipeg - From Monday's Globe and Mail

http://www.theglobeandmail.com/news/technology/science/study-prompts-provinces-to-rethink-flu-plan/article1303330/

A "perplexing" Canadian study linking H1N1 to seasonal flu shots is 
throwing national influenza plans
into disarray and testing public faith in the government agencies 
responsible for protecting the nation's health.

Distributed for peer review last week, the study confounded 
infectious-disease experts in suggesting that people vaccinated 
against seasonal flu are twice as likely to catch swine flu.

The paper is under peer review, and lead researchers Danuta 
Skowronski of the British Columbia Centre
for Disease Control and Gaston De Serres of Laval University must 
stay mum until it's published.

Met with intense early skepticism both in Canada and abroad, the 
paper has since convinced several provincial health agencies to 
announce hasty suspensions of seasonal flu vaccinations, long-held 
fixtures
of public-health planning.

"It has confused things very badly," said Dr. Ethan Rubinstein, head 
of adult infectious diseases at the University of Manitoba. "And it 
has certainly cost us credibility from the public because of 
conflicting recommendations. Until last week, there had always been 
much encouragement to get the seasonal
flu vaccine."

On Sunday Quebec joined Alberta, Saskatchewan, Ontario and Nova 
Scotia in suspending seasonal flu shots for anyone under 65 years of 
age. Quebec's Health Ministry announced it would postpone 
vaccinations until January, clearing the autumn months for health 
professionals to focus on vaccinating
against H1N1, which is expected to the more severe influenza strain 
this season.

"By the time the H1N1 wave is over, there will be ample time to 
vaccinate for seasonal flu," Dr.
Rubinstein said.

B.C. is expected to announce a similar suspension during a press 
conference Monday morning.

Other provinces, including Manitoba, are still pondering a response 
to the research.

New Brunswick is a lone hold-out, announcing last week it would forge 
ahead with seasonal flu shots
for all residents in October, as originally planned.

So far, the study's impact is confined to Canada. Researchers in the 
U.S., Britain and Australia have not reported the same phenomenon. 
Marie-Paule Kieny, the World Health Organization's director of 
vaccine research, said last week the Canadian findings were an 
international anomaly and could constitute a "study bias."

An international panel is currently scrutinizing the research data. 
"The review process has been
expedited, so we're hoping for a response within days," said Roy 
Wadia, spokesman for the B.C. Centre
for Disease Control.

Dr. Rubinstein, who has read the study, said it appears sound.

"There are a large number of authors, all of them excellent and 
credible researchers," he said. "And the sample size is very large - 
12 or 13 million people taken from the central reporting systems in 
three provinces. The research is solid."

The vaccine suspensions do not apply for people over 65. Seniors are 
considered more susceptible to
severe seasonal flu symptoms. At the same time, they carry antibodies 
from a 1957 pandemic that
seem to neutralize the current version of H1N1.

Even if the statistical link is proven, the medical link between 
seasonal flu shots and H1N1 remains mysterious. One hypothesis 
suggests seasonal flu vaccine preoccupies the cells that would 
otherwise produce antibodies against H1N1.

But, according to Dr. Rubinstein, the research shows that people who 
received the seasonal shot
during the 2007-08 flu season remained vulnerable to swine flu well 
into 2009 - an interval that
should provide most immune systems ample restoration time.

"We don't understand the mechanism," Dr. Rubinstein said. "At the 
present time it is quite perplexing."
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