Buongiorno nexiane,

sarà OT qui?

«The illusion of evidence based medicine»
(di sicuro l'illusione non è limitata alla medicina, n.d.r)

BMJ 2022; 376
doi: https://doi.org/10.1136/bmj.o702
(Published 16 March 2022)  

https://www.bmj.com/content/376/bmj.o702

Questi alcuni estratti arbitrariamente selezionati da me, ma l'articolo
non può essere riassunto.

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Evidence based medicine has been corrupted by corporate interests,
failed regulation, and commercialisation of academia, argue these
authors

The advent of evidence based medicine was a paradigm shift intended to
provide a solid scientific foundation for medicine. The validity of this
new paradigm, however, depends on reliable data [...]

The release into the public domain of previously confidential
pharmaceutical industry documents has given the medical community
valuable insight into the degree to which industry sponsored clinical
trials are misrepresented. Until this problem is corrected,
evidence based medicine will remain an illusion.

The philosophy of critical rationalism, advanced by the philosopher Karl
Popper, famously advocated for the integrity of science and its role in
an open, democratic society. [...]

Scientific progress is thwarted by the ownership of data and knowledge
because industry suppresses negative trial results, fails to report
adverse events, and does not share raw data with the academic research
community. [...]

The pharmaceutical industry’s responsibility to its shareholders means
that priority must be given to their hierarchical power structures,
product loyalty, and public relations propaganda over scientific
integrity. [...]

As a result, university departments become instruments of industry:
through company control of the research agenda and ghostwriting of
medical journal articles and continuing medical education, academics
become agents for the promotion of commercial products. [...]

The corporate university also compromises the concept of academic
leadership. Deans who reached their leadership positions by virtue of
distinguished contributions to their disciplines have in places been
replaced with fundraisers and academic managers, who are forced to
demonstrate their profitability or show how they can attract corporate
sponsors. [...] for example, physicians are selected based on their
influence on prescribing habits of other physicians. [...] 

Ironically, industry sponsored KOLs (key opinion leaders, n.d.r.) appear
to enjoy many of the advantages of academic freedom, supported as they
are by their universities, the industry, and journal editors for
expressing their views, even when those views are incongruent with the
real evidence. While universities fail to correct misrepresentations of
the science from such collaborations, critics of industry face
rejections from journals, legal threats, and the potential destruction
of their careers. [...]

Regulators receive funding from industry and use industry funded and
performed trials to approve drugs, without in most cases seeing the raw
data. [...] Unconcerned governments and captured regulators are unlikely to 
initiate
necessary change to remove research from industry altogether and clean
up publishing models that depend on reprint revenue, advertising, and
sponsorship revenue.

Our proposals for reforms include: [...]

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Ometto le proposte di riforma degli autori (se vi interessano potete
facilmente trovarle voi) perché mi interessano veramente poco, è la
diagnosi che conta, ma che è ancora /ampiamente/ ignorata, contrastata,
misconosciuta e perfino negata: la "evidence based"-qualcosa è **una
illusione**, la scienza (la medicina è scienza?!?) è /altra cosa/ (con
buona pace di Popper e dei positivisti, ma non divaghiamo)

Saluti, 380°



P.S.: per una analisi, completa di comoda rappresentazione grafica, su
quali sono i meccanismi e gli "input" attraverso i quali si giunga alla
illusione scientifica (chiamata scientific halucination nel testo) si
veda https://nooscope.ai/

-- 
380° (Giovanni Biscuolo public alter ego)

«Noi, incompetenti come siamo,
 non abbiamo alcun titolo per suggerire alcunché»

Disinformation flourishes because many people care deeply about injustice
but very few check the facts.  Ask me about <https://stallmansupport.org>.

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