*So—for the umpteenth time—why has this urgent information not been* *publicized by CDC/Dr. Fauci/WHO, and reported by "our free press"? * *They **scream at us non-stop to wear our masks and stay six feet apart, * *to "keep us safe," and yet say **nothing **about this?*
*MCM* Vitamin D Treatment Is Associated with Reduced Risk of Mortality in Patients with COVID-19: A Cross-Sectional Multi-Centre Observational Study 17 Pages Posted: 20 Oct 2020 https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3690902 Stephanie Fenxi Ling <https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=4362443> The University of Manchester Eleanor Broad <https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=4362445> Tameside and Glossop Integrated Care NHS Foundation Trust Rebecca Murphy <https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=4438518> Tameside and Glossop Integrated Care NHS Foundation Trust Joseph Mundattuchundayil Pappachan <https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=4362446> University of Manchester Satveer Pardesi-Newton <https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=4362447> University Hospitals of Leicester NHS Trust - Leicester Royal Infirmary Marie-France Kong <https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=4362448> University Hospitals of Leicester NHS Trust - Leicester General Hospital Edward Bernard Jude <https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=4362450> Tameside and Glossop Integrated Care NHS Foundation Trust More... Abstract Background: The 2019 novel coronavirus disease (Covid-19) worldwide pandemic has posed the most substantial and severe public health issue for several generations, and therapeutic options for it have not yet been optimised. Vitamin D has been proposed in the pharmacological management of Covid-19 by various sources. This study aimed to determine whether Covid-19 disease outcomes were affected by vitamin D status, and to elucidate any predictors of Covid-19 outcomes. Methods: Patients hospitalised with Covid-19 were opportunistically recruited from three different UK hospitals and their data were collected. Logistic regression was used to determine any relationships between vitamin D status and various predictors, including mortality and ventilation, and to determine any relationships between mortality, ventilation, and various predictors. *Findings: Vitamin D status was not associated with any outcomes of Covid-19 investigated, following adjustment for age and sex. However, treatment with vitamin D was significantly associated with a reduced risk of death, following adjustment for age and sex (ORadj 0·48, 95% CI 0·32 – 0·70, p = 1·79x10-4). This relationship remained significant when also adjusted for baseline vitamin D levels (ORadj 0·47, 95% CI 0·33 – 0·70, p = 1·27x10-4).* Interpretation: Treatment with vitamin D, regardless of baseline serum vitamin D levels, appears to be associated with a reduced risk of mortality in acute in-patients admitted with Covid-19. Further work on large population studies needs to be carried out to determine adequate serum levels of vitamin D, as well as multi-dose clinical trials of vitamin D treatment to assess maximum efficacy. Trial Registration: The study was also registered on Clinicaltrials.gov (reference number NCT04386044), prior to commencement. Funding: None. Declaration of Interests: The authors have no conflicts of interest. Ethics Approval Statement: Ethical approval was granted by the Health and Care Research Wales Research Ethics Committee (IRAS number 285337). Keywords: COVID-19, SARS-CoV-2, 2019 novel coronavirus, severe acute respiratory syndrome coronavirus 2, vitamin D, cholecalciferol, 25-hydroxyvitamin D, mortality, death, invasive ventilation, intubation, endotrachel intubation, continuous positive airways pressure, CPAP Suggested Citation: --- Support News from Underground: https://bit.ly/NFUSupport Visit News from Underground: https://markcrispinmiller.com You received this email because you are subscribed to News from Underground. To unsubscribe from this email list, please go to: http://www.simplelists.com/confirm.php?u=pIdjNUgiG2h8yxbhC54SSy4SEskAoEMs For archives, please go to: https://archives.simplelists.com/nfu
