Blender is preparing to become a GUI Framework, and it can already easily do complex GUI with ready-made themable widgets, 2D/3D, PBR, CPU/GPU, Raytracing, VR/AR, shaders, openGL, 3D sound, network, camera, sockets, IO, video, mobile planned, visually outperforms QtGL, we already have wrapper.
Right now that does not exist yet, but has an Epic MegaGrant for it. <https://youtu.be/S_C_kvFQ-lY>