Dear All,
Could anyone help me to interpret ETAbar p value? I have:
TOT. NO. OF OBS RECS: 1486
TOT. NO. OF INDIVIDUALS: 213
ETABAR: -0.52E-02 -0.27E-01 -0.93E-01
P VAL.: 0.90E+00 0.24E+00 0.81E-04
ETA1 ETA2 ETA3
ETA1 4.08E-01
ETA2 2.26E-01 2.31E-01
ETA3 0.00E+00 0.00E+00 9.70E-01
which looks too low for me for eta3. I checked that p of abs(mean(eta)) > 0.093
is about 0.17 for
normally distributed variable with SD=sqrt(0.97) and about 200 patients.
sum1 <- 0
for(i in 1:1000000) if(abs(mean(rnorm(213,0,sqrt(0.97))))> 0.093) sum1 <-
sum1+1
print(sum1/1000000)
[1] 0.168624
How exactly this p-value is computed (NONMEM V) ?
Thanks
Leonid
