I am not an expert in NO0NMEM but may be you need to request the posthoc IN THE $EST .
Best; Serge Guzy ________________________________ From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of yyzjyhs Sent: Tuesday, April 01, 2008 6:28 AM To: [email protected] Subject: [NMusers] hlep Importance: High Name YanYun Title range for CL is zero,scatterplot omitted Organization College of Veterinary medicine,South China Agriculture University E-mail Address [EMAIL PROTECTED] Phone Number 13560250188 City GuangZhou State GuangDong Province Postal Code 510642 Country China Nature of Problem Dear All, Thanks for your help. I am a novice in using NONMEM. I am working on a PPK model.My control is: $PROB THEOPHYLLINE POPULATION DATA $INPUT ID DOSE=AMT TIME CP=DV WT SEX AGE AST ALT ALP TP CREA ALB GGT TBIL DBIL $DATA YUANCHI $SUBROUTINES ADVAN3 TRANS4 $PK CL=THETA(1)+ETA(1) V1=THETA(2)+ETA(2) Q=THETA(3)+ETA(3) V2=THETA(4)+ETA(4) K=CL/V1 K12=Q/V1 K21=Q/V2 SC=V1 $THETA (0,1,100) (0,1,100) (0,3,100) (0,5,100) $OMEGA .04 .04 1 1 $ERROR Y=F+EPS(1) $SIGMA .1 $EST MAXEVAL=9999 PRINT=50 $COV $SCAT CL VS (WT SEX AGE AST ALT ALP TP CREA ALB GGT TBIL DBIL) $SCAT (CP PRED) VS TIME $SCAT CP VS PRED UNIT it return "range for CL is zero,scatterplot omitted",and I try "CL=THETA(1)*EXP(ETA(1))" "CL=THETA(1)*(1+ETA(1)) ,too.It still show "orange for CL is zero,scatterplot omitted. what should I do? Thanks, YanYun ________________________________ 开启健康，赢取大奖 <http://popme.163.com/link/004156_0328_7071.html> -- The information contained in this email message may contain confidential or legally privileged information and is intended solely for the use of the named recipient(s). No confidentiality or privilege is waived or lost by any transmission error. If the reader of this message is not the intended recipient, please immediately delete the e-mail and all copies of it from your system, destroy any hard copies of it and notify the sender either by telephone or return e-mail. Any direct or indirect use, disclosure, distribution, printing, or copying of any part of this message is prohibited. Any views expressed in this message are those of the individual sender, except where the message states otherwise and the sender is authorized to state them to be the views of XOMA.
