There are many possible data record error messages. What was the specific error message?
________________________________ From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Yuyan Jin Sent: Tuesday, May 27, 2008 10:53 AM To: [email protected] Subject: [NMusers] multiple dose with unequal dosing intervals Hi All, I am trying to analyze a multiple dose oral PK data (with unequal dosing intervals) using NONMEM. second dose is given 48 hrs after the first dose and after that the drug is given on 12 hr dosing interval over 14 days. There are 8 sampling points available in first 48 h and then one trough sample is available after 7 days, and following last dose, 8 data points are available for next 24 h. the following is a representative of my data set #ID TIME DV AMT ADDL II MDV 102 0 0 60 0 48 1 102 0.5 205 0 0 0 0 102 1 305 0 0 0 0 102 2 283 0 0 0 0 102 4 134 0 0 0 0 102 6 78.8 0 0 0 0 102 8 51.5 0 0 0 0 102 12 17.6 0 0 0 0 102 24 2.16 0 0 0 0 102 48 0 60 30 12 1 102 192 704 0 0 0 0 102 360 585 0 0 0 0 102 360.5 782 0 0 0 0 102 361 1070 0 0 0 0 102 362 1460 0 0 0 0 102 364 1270 0 0 0 0 102 366 965 0 0 0 0 102 368 652 0 0 0 0 102 372 433 0 0 0 0 my model is not runing due to data record error message, Can anybody please help me setting up the data file? Any inputs will be appreciated. Thanks a lot, Yuyan graduate student ICON plc made the following annotations. ------------------------------------------------------------------------------ This e-mail transmission may contain confidential or legally privileged information that is intended only for the individual or entity named in the e-mail address. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution, or reliance upon the contents of this e-mail is strictly prohibited. If you have received this e-mail transmission in error, please reply to the sender, so that ICON plc can arrange for proper delivery, and then please delete the message. Thank You, ICON plc South County Business Park Leopardstown Dublin 18 Ireland Registered number: 145835
